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Indian J Clin Biochem. 2001 Jul;16(2):199-202. doi: 10.1007/BF02864861.

Serum oestradiol in women with carcinomas of the breast and uterine cervix.

Indian journal of clinical biochemistry : IJCB

A Ray, A K Bahadur, S L Dayalu Naik, B K Sharma

Affiliations

  1. Institute of Cytology and Preventive Oncology (ICMR), Maulana Azad Medical College, 110002 New Delhi.

PMID: 23105318 PMCID: PMC3453627 DOI: 10.1007/BF02864861

Abstract

Endogenous oestrogens are thought to be involved in breast cancer, but few studies could show the direct relationship between hormones and pathological process of the disease. In the present study, oestradiol was estimated in the serum of pre-and postmenopausal breast cancer patients along with normal healthy controls and patients with carcinoma of the uterine cervix which is not dependent on oestrogens. Premenopausal patients with breast cancer showed higher levels of oestradiol as compared to premenopausal control women as well as cervical cancer patients. Whereas, no statistically significant differences were observed in serum oestradiol levels amongst postmenopausal groups of breast cancer, cervical cancer and normal women. The result of the study reflects the association of oestradiol as well as its difference in the pathological events of pre and postmenopausal breast cancer.

Keywords: Oestradiol; breast cancer; cervical cancer; menopausal status

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