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Indian J Clin Biochem. 2005 Jul;20(2):81-5. doi: 10.1007/BF02867405.

Correlation between chemical components of billary calculi and bile & sera and bile of gallstone patients.

Indian journal of clinical biochemistry : IJCB

Prasheeda Chandran, Pradeep Garg, Chandra S Pundir

Affiliations

  1. Biochemistry Research Laboratory, Department of Bio-Sciences, M.D. University, 124 001 Rohtak, Haryana India.

PMID: 23105538 PMCID: PMC3453830 DOI: 10.1007/BF02867405

Abstract

Total cholesterol, total bilirubin, calcium, oxalate, inorganic phosphate, magnesium, iron, copper, sodium and potassium were analyzed quantitatively in gallstones, bile of gall bladder and sera of 200 patients of cholelithiasis (52 cholesterol, 76 mixed and 72 pigment stone patients) and their contents were correlated between calculi and bile and sera and bile in these three type of stone patients. A significant positive correlation was observed between total cholesterol, total bilirubin of calculi and bile, copper of bile and sera of cholesterol stone patients, copper of calculi and bile, total bilirubin, oxalate, magnesium, potassium of sera and bile of pigment stone patients and oxalate and iron of stone and bile, total bilirubin, oxalate, sodium of sera and bile of mixed stone patients. A significant negative correlation was found between magnesium of serum and bile of cholesterol stone patients, oxalate of calculi and bile of pigment stone patients and magnesium of serum and bile of mixed stone patients.

Keywords: Bile; Biliary calculi; Chemical Composition Trace metals; Cholelithiasis; Gallstone; Serum

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