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Ohnaka K, Ikeda M, Maki T, et al. Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial. J Nutr Metab. 2012;2012:207426doi: 10.1155/2012/207426.
Ohnaka, K., Ikeda, M., Maki, T., Okada, T., Shimazoe, T., Adachi, M., Nomura, M., Takayanagi, R., & Kono, S. (2012). Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial. Journal of nutrition and metabolism, 2012207426. https://doi.org/10.1155/2012/207426
Ohnaka, Keizo, et al. "Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial." Journal of nutrition and metabolism vol. 2012 (2012): 207426. doi: https://doi.org/10.1155/2012/207426
Ohnaka K, Ikeda M, Maki T, Okada T, Shimazoe T, Adachi M, Nomura M, Takayanagi R, Kono S. Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial. J Nutr Metab. 2012;2012:207426. doi: 10.1155/2012/207426. Epub 2012 Nov 05. PMID: 23193459; PMCID: PMC3502017.
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J Nutr Metab. 2012;2012:207426. doi: 10.1155/2012/207426. Epub 2012 Nov 05.

Effects of 16-week consumption of caffeinated and decaffeinated instant coffee on glucose metabolism in a randomized controlled trial.

Journal of nutrition and metabolism

Keizo Ohnaka, Mizuko Ikeda, Takako Maki, Tomoko Okada, Takao Shimazoe, Masahiro Adachi, Masatoshi Nomura, Ryoichi Takayanagi, Suminori Kono

Affiliations

  1. Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

PMID: 23193459 PMCID: PMC3502017 DOI: 10.1155/2012/207426

Abstract

Objective. Observational studies have shown a protective association between coffee consumption and type 2 diabetes mellitus whereas caffeine or caffeinated coffee acutely deteriorates glucose tolerance. We investigated the effects of chronic drinking of instant coffee on glucose and insulin concentrations during a 75 g oral glucose tolerance test. Methods. Overweight men with a mild-to-moderate elevation of fasting plasma glucose were randomly allocated to a 16-week intervention of consuming 5 cups of caffeinated (n = 17) or decaffeinated (n = 15) instant coffee per day or no coffee (n = 13). Results. The caffeinated coffee group showed statistically significant decreases in the 2-hour concentrations and the area under the curve of glucose while neither decaffeinated coffee nor coffee group showed such a change. Waist circumstance decreased in the caffeinated coffee group, increased in the decaffeinated coffee group, and did not change in the noncoffee group (P = 0.002). With adjustment for the change in waist circumference, caffeinated and decaffeinated coffee consumption were associated with a modest decrease in the postload glucose levels. Conclusion. Both caffeinated and decaffeinated coffee may be protective against deterioration of glucose tolerance.

References

  1. Diabetes. 2001 Oct;50(10):2349-54 - PubMed
  2. Am J Clin Nutr. 2004 Jul;80(1):22-8 - PubMed
  3. Am J Clin Nutr. 2010 Apr;91(4):950-7 - PubMed
  4. Arch Intern Med. 2006 Jun 26;166(12):1311-6 - PubMed
  5. Nutr J. 2011 Sep 13;10:93 - PubMed
  6. Am J Clin Nutr. 2006 Oct;84(4):888-93 - PubMed
  7. Eur J Clin Pharmacol. 2000 May;56(2):153-8 - PubMed
  8. Am J Clin Nutr. 2008 May;87(5):1254-61 - PubMed
  9. Metabolism. 2007 Dec;56(12):1694-8 - PubMed
  10. Am J Clin Nutr. 2006 Mar;83(3):674-80 - PubMed
  11. Obesity (Silver Spring). 2007 Feb;15(2):349-55 - PubMed
  12. Biochem Biophys Res Commun. 1999 Apr 2;257(1):79-83 - PubMed
  13. Diabetes Care. 2008 Mar;31(3):504-7 - PubMed
  14. J Oleo Sci. 2008;57(12):691-7 - PubMed
  15. J Med Chem. 1997 Jan 17;40(2):137-45 - PubMed
  16. Can J Physiol Pharmacol. 2001 Jul;79(7):559-65 - PubMed
  17. JAMA. 2005 Jul 6;294(1):97-104 - PubMed
  18. Diabetologia. 2004 Dec;47(12):2152-9 - PubMed
  19. Am J Clin Nutr. 2003 Oct;78(4):728-33 - PubMed
  20. Metabolism. 2012 Sep;61(9):1231-7 - PubMed
  21. Diabetologia. 2004 Dec;47(12):2145-51 - PubMed
  22. Arch Intern Med. 2009 Dec 14;169(22):2053-63 - PubMed
  23. Am J Clin Nutr. 2004 Oct;80(4):862-7 - PubMed
  24. Ann Intern Med. 2004 Jan 6;140(1):1-8 - PubMed
  25. J Agric Food Chem. 2011 Dec 28;59(24):13147-55 - PubMed
  26. Pharmacogenetics. 2001 Jul;11(5):429-35 - PubMed
  27. Diabetes Care. 2008 Feb;31(2):221-2 - PubMed
  28. Diabetes Care. 2006 Feb;29(2):398-403 - PubMed
  29. Am J Clin Nutr. 2006 Oct;84(4):682-93 - PubMed
  30. Diabetes Care. 2002 Feb;25(2):364-9 - PubMed
  31. Diabetes Care. 1999 Sep;22(9):1462-70 - PubMed
  32. J Nutr. 2004 Oct;134(10):2528-33 - PubMed
  33. J Nutr. 2006 May;136(5):1276-80 - PubMed
  34. Can J Physiol Pharmacol. 2007 Aug;85(8):823-30 - PubMed
  35. Diabetologia. 1985 Jul;28(7):412-9 - PubMed
  36. J Lipid Res. 2006 Jul;47(7):1572-82 - PubMed
  37. Scand J Clin Lab Invest. 2000 Feb;60(1):37-43 - PubMed
  38. Yakugaku Zasshi. 2010 May;130(5):713-5 - PubMed
  39. Diabetes Care. 2004 Dec;27(12):2990-2 - PubMed

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