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J Bronchology Interv Pulmonol. 2011 Apr;18(2):161-3. doi: 10.1097/LBR.0b013e31821713e8.

Primary tracheomalacia and persistent wheezing in cystic fibrosis during infancy.

Journal of bronchology & interventional pulmonology

Woolf Walker, Claire Head, Julian Legg, Gary Connett

Affiliations

  1. Regional Paediatric Cystic Fibrosis Unit, Southampton University Hospitals Trust, Southampton General Hospital, Southampton, UK.

PMID: 23169087 DOI: 10.1097/LBR.0b013e31821713e8

Abstract

Persistent wheezing, poorly responsive to bronchodilator therapy, raises concerns about the progression of cystic fibrosis-related lung disease. We describe 3 infants with such symptoms who were observed to have primary tracheomalacia. The diagnoses were made using flexible bronchoscopy during spontaneous respiration. Early recognition of this etiology can limit unnecessary investigation and the overuse of empirical treatments such as oral and inhaled corticosteroids.

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