Display options
Cite
Eskandari S, Azimzadeh A, Bahar M, et al. Efficacy of Microwave and Infrared Radiation in the Treatment of the Skin Lesions Caused by Leishmania major in an Animal Model. Iran J Public Health. 2012;41(8):80-3
Eskandari, S., Azimzadeh, A., Bahar, M., Naraghi, Z. S., Javadi, A., Khamesipour, A., & Mohamadi, A. M. (2012). Efficacy of Microwave and Infrared Radiation in the Treatment of the Skin Lesions Caused by Leishmania major in an Animal Model. Iranian journal of public health, 41(8), 80-3.
Eskandari, Se, et al. "Efficacy of Microwave and Infrared Radiation in the Treatment of the Skin Lesions Caused by Leishmania major in an Animal Model." Iranian journal of public health vol. 41,8 (2012): 80-3.
Eskandari S, Azimzadeh A, Bahar M, Naraghi ZS, Javadi A, Khamesipour A, Mohamadi AM. Efficacy of Microwave and Infrared Radiation in the Treatment of the Skin Lesions Caused by Leishmania major in an Animal Model. Iran J Public Health. 2012;41(8):80-3. Epub 2012 Aug 31. PMID: 23113229; PMCID: PMC3469029.
Copy Download .nbib Format: NLM
Share it on

Iran J Public Health. 2012;41(8):80-3. Epub 2012 Aug 31.

Efficacy of Microwave and Infrared Radiation in the Treatment of the Skin Lesions Caused by Leishmania major in an Animal Model.

Iranian journal of public health

Se Eskandari, A Azimzadeh, M Bahar, Z Safai Naraghi, A Javadi, A Khamesipour, A Miramin Mohamadi

Affiliations

  1. Center for Research & Training in Skin Diseases & Leprosy, Tehran University of Medical Sciences, Tehran, Iran.

PMID: 23113229 PMCID: PMC3469029

Abstract

BACKGROUND: Cutaneous leishmaniasis caused by L. major is an important public health problem in endemic areas. The aim of this study was to explore the therapeutic effect of microwave and or infrared radiation in the treatment of lesion induced in BALB/c mice by L. major inoculation.

METHODS: The footpad lesion was induced in BALB/c mice by inoculation of L. major promastigotes subcutaneously. The lesion was treated with 600 watts power, 2.450 GHz frequency and/or infrared device with 150 watts and a wave length of 890 nanometres. The size of the lesion was recorded by footpad swelling measurement every 10 days.

RESULTS: The lesion growth was significantly hampered in treated mice compared with the untreated control group (P<0.05). Infrared radiation was more effective than microwave in inhibiting ulcer enlargement.

CONCLUSION: Infrared radiation and microwave significantly hampered L. major lesion growth in BALB/c mice. This therapeutic effect was more in infrared radiation treated mice than microwave treated mice.

Keywords: Infrared; Leishmania major; Microwave; Mouse

References

  1. Int J Antimicrob Agents. 2010 Nov;36 Suppl 1:S62-5 - PubMed
  2. J Surg Res. 1994 Dec;57(6):667-71 - PubMed
  3. Ann Inst Pasteur Immunol. 1987 Sep-Oct;138(5):744-9 - PubMed
  4. J Am Coll Surg. 1997 Jan;184(1):37-43 - PubMed
  5. PLoS Med. 2006 May;3(5):e162 - PubMed
  6. Am J Surg. 1995 Sep;170(3):271-6 - PubMed
  7. Lancet. 1999 Nov 27;354(9193):1859-63 - PubMed
  8. J Am Acad Dermatol. 2007 Aug;57(2):335.e1-29 - PubMed
  9. Lancet. 1999 Oct 2;354(9185):1191-9 - PubMed
  10. Mil Med. 2012 Mar;177(3):345-51 - PubMed
  11. Clin Dermatol. 1999 May-Jun;17(3):291-6 - PubMed
  12. Bioelectromagnetics. 2010 May;31(4):318-23 - PubMed
  13. Clin Dermatol. 1996 Sep-Oct;14(5):425-31 - PubMed
  14. Kinetoplastid Biol Dis. 2007 Apr 24;6:3 - PubMed

Publication Types