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Stoimenis D, Spyridonidou C, Papaioannou N. Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection. Case Rep Med. 2012;2012:607104doi: 10.1155/2012/607104.
Stoimenis, D., Spyridonidou, C., & Papaioannou, N. (2012). Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection. Case reports in medicine, 2012607104. https://doi.org/10.1155/2012/607104
Stoimenis, Dimitrios, et al. "Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection." Case reports in medicine vol. 2012 (2012): 607104. doi: https://doi.org/10.1155/2012/607104
Stoimenis D, Spyridonidou C, Papaioannou N. Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection. Case Rep Med. 2012;2012:607104. doi: 10.1155/2012/607104. Epub 2012 Nov 29. PMID: 23304158; PMCID: PMC3523343.
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Case Rep Med. 2012;2012:607104. doi: 10.1155/2012/607104. Epub 2012 Nov 29.

Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection.

Case reports in medicine

Dimitrios Stoimenis, Christina Spyridonidou, Nikos Papaioannou

Affiliations

  1. 1st Department of Internal Medicine, "Georgios Papanikolaou" General Hospital, Exochi, 570 10 Thessaloniki, Greece.

PMID: 23304158 PMCID: PMC3523343 DOI: 10.1155/2012/607104

Abstract

Monoclonal gammopathy reflects a serological disorder suggesting a plasma cell dyscrasia or a B-cell abnormality. However, it may occasionally be encountered as a transient manifestation in the course of several diseases including infections. This is the first reported case of a transient monoclonal gammopathy IgG lambda light chain associated with a Staphylococcus aureus infection that was complicated with renal abscess and vertebral spondylodiscitis in a previously healthy 68-year-old male. We observed a complete resolution of the gammopathy within three months of medical treatment before the entire restoration of all clinical and laboratory findings. Many invasive and cost-intensive diagnostic procedures had preceded the exclusion of a malignancy. The clinical significance and the exact pathogenesis of transient monoclonality are poorly understood and remain a matter of speculation.

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