Display options
Cite
Souza-Machado A, Santos PM, Cruz AA. Adherence to treatment in severe asthma: predicting factors in a program for asthma control in Brazil. World Allergy Organ J. 2010;3(3):48-52doi: 10.1097/WOX.0b013e3181d25e8e.
Souza-Machado, A., Santos, P. M., & Cruz, A. A. (2010). Adherence to treatment in severe asthma: predicting factors in a program for asthma control in Brazil. The World Allergy Organization journal, 3(3), 48-52. https://doi.org/10.1097/WOX.0b013e3181d25e8e
Souza-Machado, Adelmir, et al. "Adherence to treatment in severe asthma: predicting factors in a program for asthma control in Brazil." The World Allergy Organization journal vol. 3,3 (2010): 48-52. doi: https://doi.org/10.1097/WOX.0b013e3181d25e8e
Souza-Machado A, Santos PM, Cruz AA. Adherence to treatment in severe asthma: predicting factors in a program for asthma control in Brazil. World Allergy Organ J. 2010 Mar;3(3):48-52. doi: 10.1097/WOX.0b013e3181d25e8e. PMID: 23282417; PMCID: PMC3651054.
Copy Download .nbib Format: NLM
Share it on

World Allergy Organ J. 2010 Mar;3(3):48-52. doi: 10.1097/WOX.0b013e3181d25e8e.

Adherence to treatment in severe asthma: predicting factors in a program for asthma control in Brazil.

The World Allergy Organization journal

Adelmir Souza-Machado, Pablo Moura Santos, Alvaro A Cruz

Affiliations

  1. From the 1Instituto de Ciências da Saúde, 2 ProAR, Hospital Universitário Professor Edgar Santos, and 3ProAR, Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Bahia, Brazil.

PMID: 23282417 PMCID: PMC3651054 DOI: 10.1097/WOX.0b013e3181d25e8e

Abstract

BACKGROUND: : In Brazil, like many other low- to middle-income countries, most asthmatic patients cannot afford the medication necessary to prevent exacerbations. The reference clinic of the Programme for Asthma Control in Bahia (ProAR; Salvador-Bahia) offers free medical care, pharmaceutical assistance (inhaled medication) and patient education. The reference clinic is accessible to all the population of Salvador and the Programme is targeted on severe asthma.

OBJECTIVE: : The aim of the present study was to evaluate adherence to inhaled medication in severe asthmatics enrolled in ProAR.

METHODS: : A sub-group of 160 consecutive severe asthmatics enrolled in ProAR were followed prospectively for 6 months. All patients were assessed by means the Asthma Control Questionnaire, the Beck Depression Inventory and spirometry. The rate of adherence to inhaled corticosteroid was checked monthly. A cut-off point of 80% of the doses prescribed in the period was used to define patients as adherent.

RESULTS: : Of the one hundred-sixty patients with severe asthma included, it was possible to objectively assess adherence to the use of the inhaled corticosteroid in 158. Among these, 112 (70.9%) were considered adherent according to the adopted cut-off point. The rate of adherence in the whole sample of subjects was 83.9% of the prescribed doses. There was a significant association between asthma control and adherence to treatment. Predictors of poor adherence were adverse effects, living far from the referral center, limited resources to pay for transportation and dose schedule.

CONCLUSION: : In the present study, adherence to treatment was high. In a sample of patients with severe asthma managed in a public program that provides free medication and multidisciplinary treatment at a referral center, adherence to treatment was found to be associated with favorable clinical outcomes.

References

  1. Arch Gen Psychiatry. 1961 Jun;4:561-71 - PubMed
  2. Clin Ther. 2001 Aug;23(8):1296-310 - PubMed
  3. Respir Med. 2001 Jan;95(1):37-9 - PubMed
  4. J Bras Pneumol. 2006 Jul-Aug;32(4):277-83 - PubMed
  5. Eur Respir J. 1999 Oct;14(4):902-7 - PubMed
  6. J Bras Pneumol. 2008 Dec;34(12):995-1002 - PubMed
  7. Eur Respir J. 1995 Jun;8(6):899-904 - PubMed
  8. Drugs. 1996;52 Suppl 6:12-9 - PubMed
  9. Am J Respir Crit Care Med. 1994 Feb;149(2 Pt 2):S69-76; discussion S77-8 - PubMed
  10. J Allergy Clin Immunol. 1997 Jun;99(6 Pt 1):773-80 - PubMed
  11. BMJ. 1993 Oct 2;307(6908):846-8 - PubMed
  12. N Engl J Med. 2005 Aug 4;353(5):487-97 - PubMed
  13. Med J Aust. 2003 May 5;178(9):437-41 - PubMed
  14. J Asthma. 2007 Oct;44(8):593-8 - PubMed
  15. West Afr J Med. 2008 Jul;27(3):155-9 - PubMed
  16. J Bras Pneumol. 2007 Jan-Feb;33(1):15-9 - PubMed
  17. Med Care. 1984 Oct;22(10):912-21 - PubMed
  18. Med Care. 2001 Dec;39(12):1326-38 - PubMed

Publication Types