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Iacoangeli M, Di Rienzo A, Re M, et al. Endoscopic endonasal approach for the treatment of a large clival giant cell tumor complicated by an intraoperative internal carotid artery rupture. Cancer Manag Res. 2013;5:21-4doi: 10.2147/CMAR.S38768.
Iacoangeli, M., Di Rienzo, A., Re, M., Alvaro, L., Nocchi, N., Gladi, M., De Nicola, M., & Scerrati, M. (2013). Endoscopic endonasal approach for the treatment of a large clival giant cell tumor complicated by an intraoperative internal carotid artery rupture. Cancer management and research, 521-4. https://doi.org/10.2147/CMAR.S38768
Iacoangeli, Maurizio, et al. "Endoscopic endonasal approach for the treatment of a large clival giant cell tumor complicated by an intraoperative internal carotid artery rupture." Cancer management and research vol. 5 (2013): 21-4. doi: https://doi.org/10.2147/CMAR.S38768
Iacoangeli M, Di Rienzo A, Re M, Alvaro L, Nocchi N, Gladi M, De Nicola M, Scerrati M. Endoscopic endonasal approach for the treatment of a large clival giant cell tumor complicated by an intraoperative internal carotid artery rupture. Cancer Manag Res. 2013;5:21-4. doi: 10.2147/CMAR.S38768. Epub 2013 Jan 30. PMID: 23403482; PMCID: PMC3565560.
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Cancer Manag Res. 2013;5:21-4. doi: 10.2147/CMAR.S38768. Epub 2013 Jan 30.

Endoscopic endonasal approach for the treatment of a large clival giant cell tumor complicated by an intraoperative internal carotid artery rupture.

Cancer management and research

Maurizio Iacoangeli, Alessandro Di Rienzo, Massimo Re, Lorenzo Alvaro, Niccolò Nocchi, Maurizio Gladi, Maurizio De Nicola, Massimo Scerrati

Affiliations

  1. Department of Neurosurgery, Università Politecnica delle Marche, Umberto I General Hospital, Ancona, Italy.

PMID: 23403482 PMCID: PMC3565560 DOI: 10.2147/CMAR.S38768

Abstract

Giant cell tumors (GCTs) are primary bone neoplasms that rarely involve the skull base. These lesions are usually locally aggressive and require complete removal, including the surrounding apparently healthy bone, to provide the best chance of cure. GCTs, as well as other lesions located in the clivus, can nowadays be treated by a minimally invasive fully endoscopic extended endonasal approach. This approach ensures a more direct route to the craniovertebral junction than other possible approaches (transfacial, extended lateral, and posterolateral approaches). The case reported is a clival GCT operated on by an extended endonasal approach that provides another contribution on how to address one of the most feared complications attributed to this approach: a massive bleed due to an internal carotid artery injury.

Keywords: clival giant cell tumor; endoscopic endonasal approach; internal carotid artery injury; minimally invasive surgery

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