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Moon JS, Yoon JS, Won KC, et al. Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes. Diabetes Metab J. 2013;37(1):54-62doi: 10.4093/dmj.2013.37.1.54.
Moon, J. S., Yoon, J. S., Won, K. C., Cho, I. H., & Lee, H. W. (2013). Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes. Diabetes & metabolism journal, 37(1), 54-62. https://doi.org/10.4093/dmj.2013.37.1.54
Moon, Jun Sung, et al. "Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes." Diabetes & metabolism journal vol. 37,1 (2013): 54-62. doi: https://doi.org/10.4093/dmj.2013.37.1.54
Moon JS, Yoon JS, Won KC, Cho IH, Lee HW. Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes. Diabetes Metab J. 2013 Feb;37(1):54-62. doi: 10.4093/dmj.2013.37.1.54. Epub 2013 Feb 15. PMID: 23439730; PMCID: PMC3579153.
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Diabetes Metab J. 2013 Feb;37(1):54-62. doi: 10.4093/dmj.2013.37.1.54. Epub 2013 Feb 15.

Diagnostic Accuracy of 64-Slice MDCT Coronary Angiography for the Assessment of Coronary Artery Disease in Korean Patients with Type 2 Diabetes.

Diabetes & metabolism journal

Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Ihn-Ho Cho, Hyoung Woo Lee

Affiliations

  1. Departement of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.

PMID: 23439730 PMCID: PMC3579153 DOI: 10.4093/dmj.2013.37.1.54

Abstract

BACKGROUND: A 64-slice multidetector computed tomography (MDCT) is well known to be a useful noninvasive form of angiography for the general population, but not for certain patients with diabetes. The aim of this study was to investigate the diagnostic accuracy and usefulness of 64-slice MDCT coronary angiography for detecting coronary artery disease in Korean patients with type 2 diabetes mellitus (T2DM).

METHODS: A total of 240 patients were included, 74 of whom had type 2 diabetes (M:F=40:33; 41.8±9.5 years). We compared significant coronary stenosis (>50% luminal narrowing) in MDCT with invasive coronary angiography (ICA) by segment, artery, and patient. We also evaluated the influence of obesity and coronary calcium score on MDCT accuracy.

RESULTS: Of the 4,064 coronary segments studied, 4,062 segments (T2DM=1,109) were assessed quantitatively by both MDCT and ICA, and 706 segments (T2DM=226) were detected as a significant lesion by ICA in all patients. Sensitivity, specificity, as well as positive and negative predictive values for the presence of significant stenosis in T2DM were: by segment, 89.4%, 96.4%, 85.8%, and 97.4%, respectively; by artery (n=222), 95.1%, 92.9%, 94.4%, and 93.8%, respectively; by patients (n=74), 98.4%, 100.0%, 98.4%, and 90.0%, respectively. Regardless of presence of diabetes, there was no significant difference in diagnostic accuracy. Obesity (≥25 kg/m(2)) and coronary calcium score did not also affect the diagnostic accuracy of MDCT.

CONCLUSION: The 64-slice MDCT coronary angiography was found to have similar diagnostic accuracy with ICA, regardless of diabetes. These results suggest MDCT may be helpful to reduce unnecessary invasive studies for patients with diabetes.

Keywords: Accuracy; Coronary artery disease; Diabetes mellitus, type 2; Multidetector computed tomography

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