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Russo AE, Scalone S, Leonardi GC, et al. Paraneoplastic cerebellar degeneration associated with ovarian cancer. Oncol Lett. 2012;5(2):681-683doi: 10.3892/ol.2012.1016.
Russo, A. E., Scalone, S., Leonardi, G. C., Scalisi, A., Giorda, G., & Sorio, R. (2013). Paraneoplastic cerebellar degeneration associated with ovarian cancer. Oncology letters, 5(2), 681-683. https://doi.org/10.3892/ol.2012.1016
Russo, Alessia Erika, et al. "Paraneoplastic cerebellar degeneration associated with ovarian cancer." Oncology letters vol. 5,2 (2013): 681-683. doi: https://doi.org/10.3892/ol.2012.1016
Russo AE, Scalone S, Leonardi GC, Scalisi A, Giorda G, Sorio R. Paraneoplastic cerebellar degeneration associated with ovarian cancer. Oncol Lett. 2013 Feb;5(2):681-683. doi: 10.3892/ol.2012.1016. Epub 2012 Nov 07. PMID: 23420048; PMCID: PMC3572954.
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Oncol Lett. 2013 Feb;5(2):681-683. doi: 10.3892/ol.2012.1016. Epub 2012 Nov 07.

Paraneoplastic cerebellar degeneration associated with ovarian cancer.

Oncology letters

Alessia Erika Russo, Simona Scalone, Giulia Costanza Leonardi, Aurora Scalisi, Giorgio Giorda, Roberto Sorio

Affiliations

  1. Department of Biomedical Sciences, Section of Pathology and Oncology, Laboratory of Translational Oncology and Functional Genomics, University of Catania, Catania 95124; ; Department of Medical Oncology C, National Cancer Institute, IRCCS, Aviano 33081;

PMID: 23420048 PMCID: PMC3572954 DOI: 10.3892/ol.2012.1016

Abstract

Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.

Keywords: anti-Yo; ovarian cancer; paraneoplastic cerebellar degeneration

References

  1. Eur J Neurol. 2006 Jul;13(7):682-90 - PubMed
  2. Genes Dev. 1999 Aug 15;13(16):2087-97 - PubMed
  3. Clin Oncol (R Coll Radiol). 2001;13(6):476-9 - PubMed
  4. Ann Neurol. 1983 Dec;14(6):609-13 - PubMed
  5. Gynecol Oncol. 2005 Nov;99(2):500-3 - PubMed
  6. J Clin Pathol. 1997 Dec;50(12):975-80 - PubMed
  7. Neurology. 2000 Sep 12;55(5):713-5 - PubMed
  8. N Engl J Med. 2003 Oct 16;349(16):1543-54 - PubMed
  9. Nat Med. 1998 Nov;4(11):1321-4 - PubMed
  10. Ann Neurol. 1988 Oct;24(4):559-67 - PubMed
  11. Arch Gynecol Obstet. 2009 Jul;280(1):99-101 - PubMed
  12. Am J Phys Med Rehabil. 2003 Feb;82(2):158-62 - PubMed
  13. Brain. 2003 Jun;126(Pt 6):1409-18 - PubMed
  14. J Neurol Neurosurg Psychiatry. 1993 Jan;56(1):112 - PubMed
  15. Neurology. 1994 Dec;44(12):2412-5 - PubMed
  16. Int J Gynecol Cancer. 2001 Mar-Apr;11(2):169-71 - PubMed
  17. J Neurooncol. 1984;2(4):377-82 - PubMed
  18. Arch Intern Med. 1997 Jun 9;157(11):1258-62 - PubMed
  19. Aust N Z J Obstet Gynaecol. 2005 Feb;45(1):79-81 - PubMed
  20. Acta Neuropathol. 1996;91(5):519-25 - PubMed
  21. Gynecol Oncol. 1999 Oct;75(1):178-83 - PubMed
  22. Neurol Clin. 2003 Feb;21(1):221-47, ix - PubMed
  23. J Clin Oncol. 1997 Mar;15(3):1272-82 - PubMed
  24. Acta Neuropathol. 2011 Oct;122(4):381-400 - PubMed
  25. Oncologist. 2006 Mar;11(3):292-305 - PubMed
  26. J Neurooncol. 2003 Jun;63(2):187-90 - PubMed
  27. J Neurol. 1999 Apr;246(4):299-303 - PubMed
  28. N Engl J Med. 1990 Jun 28;322(26):1844-51 - PubMed
  29. J Neurol Sci. 2008 Sep 15;272(1-2):171-3 - PubMed
  30. J Neurol Sci. 2000 Sep 1;178(1):63-5 - PubMed
  31. Neurology. 1994 Jun;44(6):1184-5 - PubMed
  32. Neurology. 1992 Oct;42(10):1931-7 - PubMed

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