Display options
Cite
Sconfienza LM, Lacelli F, Caldiera V, et al. Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings. J Ultrasound. 2009;13(1):16-21doi: 10.1016/j.jus.2009.09.002.
Sconfienza, L. M., Lacelli, F., Caldiera, V., Perrone, N., Piscopo, F., Gandolfo, N., & Serafini, G. (2010). Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings. Journal of ultrasound, 13(1), 16-21. https://doi.org/10.1016/j.jus.2009.09.002
Sconfienza, L M, et al. "Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings." Journal of ultrasound vol. 13,1 (2010): 16-21. doi: https://doi.org/10.1016/j.jus.2009.09.002
Sconfienza LM, Lacelli F, Caldiera V, Perrone N, Piscopo F, Gandolfo N, Serafini G. Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings. J Ultrasound. 2010 Mar;13(1):16-21. doi: 10.1016/j.jus.2009.09.002. Epub 2009 Oct 02. PMID: 23396822; PMCID: PMC3553207.
Copy Download .nbib Format: NLM
Share it on

J Ultrasound. 2010 Mar;13(1):16-21. doi: 10.1016/j.jus.2009.09.002. Epub 2009 Oct 02.

Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings.

Journal of ultrasound

L M Sconfienza, F Lacelli, V Caldiera, N Perrone, F Piscopo, N Gandolfo, G Serafini

Affiliations

  1. Unit of Radiology, IRCCS Policlinico San Donato, University of Milan School of Medicine, San Donato Milanese (MI), Italy.

PMID: 23396822 PMCID: PMC3553207 DOI: 10.1016/j.jus.2009.09.002

Abstract

INTRODUCTION: To compare the diagnostic values of three-dimensional sonohysterography (3DSH), transvaginal ultrasound (TVUS), and 2-dimensional sonohysterography (2DSH) in the work-up of abnormal uterine bleeding (AUB), in particular the ability of each method to identify intracavitary lesions arising from the endometrium or uterine wall.

MATERIALS AND METHODS: 24 patients referred for AUB underwent TVUS followed by 2-D and 3-D HS in the same session. Three-dimensional data were acquired with a free-hand technique during maximal distention of the uterus. Within 10 days of the sonographic session, each patient underwent hysteroscopy, which was considered the reference standard. For each of the 3 imaging methods, we calculated sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy.

RESULTS: Hysteroscopy demonstrated the presence of an intrauterine lesion in 21/24 patients (87.5%). In 3/24 patients hysteroscopy was negative. For TVUS, 2DSH, and 3DSH, sensitivity was 76% (16/21), 90% (19/21), 100% (21/21), respectively; specificity was 100% (3/3), 100% (19/19), 100% (21/21); PPV was 100%, 100%, 100%; NPV was 37%, 60%, 100%; accuracy was 76%, 90%, 100%.

CONCLUSIONS: 3DSH is more sensitive that 2DSH or TVUS in the detection of intrauterine lesions. If these preliminary results are confirmed in larger studies, 3DSH could be proposed as a valuable alternative to diagnostic hysteroscopy.

Keywords: Abnormal uterine bleeding; Hysteroscopy; Sonohysterography; Three-dimensional sonohysterography

References

  1. Am J Obstet Gynecol. 1995 Feb;172(2 Pt 1):547-52 - PubMed
  2. Fertil Steril. 2003 May;79(5):1222-5 - PubMed
  3. Clin Exp Obstet Gynecol. 1999;26(3-4):171-3 - PubMed
  4. J Int Med Res. 2008 Nov-Dec;36(6):1205-13 - PubMed
  5. Ultrasound Obstet Gynecol. 1997 Jan;9(1):53-8 - PubMed
  6. Gynecol Oncol. 1997 May;65(2):245-52 - PubMed
  7. AJR Am J Roentgenol. 2002 Jan;178(1):129-33 - PubMed
  8. J Clin Ultrasound. 2004 Sep;32(7):348-53 - PubMed
  9. Fertil Steril. 2000 Feb;73(2):406-11 - PubMed
  10. J Ultrasound Med. 1995 Dec;14(12):887-93 - PubMed
  11. Best Pract Res Clin Obstet Gynaecol. 2007 Dec;21(6):891-903 - PubMed
  12. BJOG. 2003 Oct;110(10):938-47 - PubMed
  13. Croat Med J. 2000 Sep;41(3):262-5 - PubMed
  14. J Minim Invasive Gynecol. 2006 Nov-Dec;13(6):505-9 - PubMed
  15. J Am Coll Radiol. 2008 Nov;5(11):1154-6 - PubMed
  16. Obstet Gynecol. 1996 Mar;87(3):345-9 - PubMed
  17. J Am Assoc Gynecol Laparosc. 1995 Nov;3(1):1-2 - PubMed
  18. Hum Reprod. 2005 Jan;20(1):253-7 - PubMed
  19. Fertil Steril. 2003 Apr;79(4):998-1002 - PubMed
  20. Radiographics. 1995 May;15(3):501-14; discussion 515-6 - PubMed
  21. Gynecol Obstet Fertil. 2002 Nov;30(11):882-9 - PubMed
  22. Ultrasound Obstet Gynecol. 1998 May;11(5):337-42 - PubMed

Publication Types