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Lozanova P, Dourmishev L, Vassileva S, et al. Perforating disseminated necrobiosis lipoidica diabeticorum. Case Rep Dermatol Med. 2013;2013:370361doi: 10.1155/2013/370361.
Lozanova, P., Dourmishev, L., Vassileva, S., Miteva, L., & Balabanova, M. (2013). Perforating disseminated necrobiosis lipoidica diabeticorum. Case reports in dermatological medicine, 2013370361. https://doi.org/10.1155/2013/370361
Lozanova, Paula, et al. "Perforating disseminated necrobiosis lipoidica diabeticorum." Case reports in dermatological medicine vol. 2013 (2013): 370361. doi: https://doi.org/10.1155/2013/370361
Lozanova P, Dourmishev L, Vassileva S, Miteva L, Balabanova M. Perforating disseminated necrobiosis lipoidica diabeticorum. Case Rep Dermatol Med. 2013;2013:370361. doi: 10.1155/2013/370361. Epub 2013 Feb 25. PMID: 23533835; PMCID: PMC3596912.
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Case Rep Dermatol Med. 2013;2013:370361. doi: 10.1155/2013/370361. Epub 2013 Feb 25.

Perforating disseminated necrobiosis lipoidica diabeticorum.

Case reports in dermatological medicine

Paula Lozanova, Lyubomir Dourmishev, Snejina Vassileva, Ljubka Miteva, Maria Balabanova

Affiliations

  1. Department of Dermatology and Venereology, Medical University Sofia, Sofia, Bulgaria.

PMID: 23533835 PMCID: PMC3596912 DOI: 10.1155/2013/370361

Abstract

Perforating necrobiosis lipoidica is a very rare clinical variant which consists of degeneration and transepidermal elimination of the collagen with few cases reported in the literature. In two-thirds of the patients it associates with diabetes, with no relation with the glucose control. We present a 42-year-old female patient with a 7-year history of diabetes on insulin therapy, referred to our clinic with a 3-year history of multiple asymptomatic firm plaques disseminated on the upper and lower extremities. The clinical and histological findings proved the diagnosis of perforating necrobiosis lipoidica.

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