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Benbrahim Z, Arifi S, Benhammane H, et al. Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel. Case Rep Oncol Med. 2013;2013:196878doi: 10.1155/2013/196878.
Benbrahim, Z., Arifi, S., Benhammane, H., Inani, K., Gallouj, S., Meziane, M., Mernissi, F. Z., Mellas, N., & El Mesbahi, O. (2013). Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel. Case reports in oncological medicine, 2013196878. https://doi.org/10.1155/2013/196878
Benbrahim, Zineb, et al. "Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel." Case reports in oncological medicine vol. 2013 (2013): 196878. doi: https://doi.org/10.1155/2013/196878
Benbrahim Z, Arifi S, Benhammane H, Inani K, Gallouj S, Meziane M, Mernissi FZ, Mellas N, El Mesbahi O. Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel. Case Rep Oncol Med. 2013;2013:196878. doi: 10.1155/2013/196878. Epub 2013 Feb 14. PMID: 23476845; PMCID: PMC3586472.
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Case Rep Oncol Med. 2013;2013:196878. doi: 10.1155/2013/196878. Epub 2013 Feb 14.

Quasi-Complete Response of Classic Kaposi's Sarcoma Treated with Weekly Paclitaxel.

Case reports in oncological medicine

Zineb Benbrahim, Samia Arifi, Hafida Benhammane, Kaoutar Inani, Salim Gallouj, Meriem Meziane, Fatima Zahra Mernissi, Nawfel Mellas, Omar El Mesbahi

Affiliations

  1. Medical Oncology, Hassan II University Hospital, P.O. Box 8743, Fès, Morocco.

PMID: 23476845 PMCID: PMC3586472 DOI: 10.1155/2013/196878

Abstract

Classic Kaposi's sarcoma (CKS) is a subtype that traditionally occurs in elderly HIV-negative males of Mediterranean origin. Patients with CKS characteristically present with skin lesions in the distal extremities. Involvement of the viscera is uncommon but may occur in the late stages of the disease. Patients with extensive KS can be treated with systemic chemotherapy. A number of drugs approved for treatment of AIDS-associated KS, especially Paclitaxel, have activity against CKS after failure of prior therapy. We report a patient treated with weekly Paclitaxel, as initial chemotherapy, for CKS presenting with multiple visceral involvement and having a contraindication for Bleomycin. The patient had quasi-complete response after three months of chemotherapy suggesting that weekly Paclitaxel might be effective as a first-line therapy for classical type KS with visceral involvement.

References

  1. Cancer. 2006 Apr 15;106(8):1785-9 - PubMed
  2. Dermatology. 2001;202(2):119-22 - PubMed
  3. Br J Dermatol. 2008 Jun;158(6):1339-44 - PubMed
  4. Cancer. 1994 Nov 15;74(10):2873-8 - PubMed
  5. Pathologe. 2004 Sep;25(5):362-74 - PubMed
  6. Anticancer Res. 2001 Jan-Feb;21(1B):571-3 - PubMed
  7. N Engl J Med. 1996 Jul 25;335(4):233-41 - PubMed
  8. J Invest Dermatol. 2008 Jun;128(6):1578-80 - PubMed
  9. Clin Oncol (R Coll Radiol). 2002 Apr;14(2):178 - PubMed
  10. J Eur Acad Dermatol Venereol. 2006 Oct;20(9):1090-4 - PubMed
  11. Int J Cancer. 1999 Jan 18;80(2):173-7 - PubMed

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