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Case Rep Pediatr. 2013;2013:931703. doi: 10.1155/2013/931703. Epub 2013 Feb 06.

Concurrent adrenal neuroblastoma and kawasaki disease: a report of a rare case.

Case reports in pediatrics

Samin Alavi, Alireza Fahimzad, Farzaneh Jadali, Farid Ghazizadeh, Armin Rashidi

Affiliations

  1. Pediatric Congenital Hematologic Disorders Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

PMID: 23476867 PMCID: PMC3580901 DOI: 10.1155/2013/931703

Abstract

Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and a leading cause of acquired heart disease. It is assumed that there is an activation of the immune system by an infectious trigger in a genetically susceptible host. Neuroblastoma is the most common extracranial solid tumor in young children. It mainly originates from primordial neural crest cells that generate the adrenal medulla and sympathetic ganglia. A diagnosis of concurrent KD and neuroblastoma in a living child has been made in only one previous report. We report the second case and review the literature.

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