Dev Cell. 2013 Mar 25;24(6):567-9. doi: 10.1016/j.devcel.2013.03.007.
Developmental cell
Hitoshi Morita, Carl-Philipp Heisenberg
PMID: 23537628 DOI: 10.1016/j.devcel.2013.03.007
In zebrafish early development, blastoderm cells undergo extensive radial intercalations, triggering the spreading of the blastoderm over the yolk cell and thereby initiating embryonic body axis formation. Now reporting in Developmental Cell, Song et al. (2013) demonstrate a critical function for EGF-dependent E-cadherin endocytosis in promoting blastoderm cell intercalations.
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