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ISRN Rheumatol. 2011;2011:840475. doi: 10.5402/2011/840475. Epub 2011 Mar 20.

Clinical and radiological presentations of late-onset spondyloarthritis.

ISRN rheumatology

Ihsane Hmamouchi, Rachid Bahiri, Najia Hajjaj-Hassouni

Affiliations

  1. Laboratory of Information and Research on Bone Diseases (LIRPOS), Department of Rheumatology, Faculty of Medicine and Pharmacy, El Ayachi Hospital, University Hospital of Rabat-Sale, University Mohammed V Souissi, Morocco ; Laboratory of Biostatistical, Clinical and Epidemiological Research (LBRCE), Faculty of Medicine and Pharmacy, University Mohammed V Souissi, Rabat, Morocco.

PMID: 23509636 PMCID: PMC3595659 DOI: 10.5402/2011/840475

Abstract

The last few years have witnessed considerable progress in the diagnosis and treatment of spondyloarthritis (SpA). Tools are now available for establishing the diagnosis at an early stage, when appropriate treatment may be able to control the inflammatory process, limit the functional impairments, and improve quality of life. Late-onset SpA after the age of 50 years is uncommon. All the spondyloarthritis subgroups are represented in the elderly. Thus, late onset spondyloarthritis is underdiagnosed in favour of other inflammatory disorders that are more frequently observed in the elderly because the clinical or radiological presentations of late-onset spondyloarthritis are modified in the elderly. They deserve further attention because age population is increasing and new criteria for axial SpA including sacroiliitis detected by MRI may help the clinician with diagnosis. Specific studies evaluating the benefit/risk ratio of TNFα-blocking agents in late onset SpA patients are required.

References

  1. Ann Rheum Dis. 1985 Jun;44(6):359-67 - PubMed
  2. J Rheumatol. 1995 May;22(5):899-903 - PubMed
  3. Joint Bone Spine. 2010 Mar;77(2):108-14 - PubMed
  4. Arthritis Rheum. 2003 Nov;48(11):3230-6 - PubMed
  5. Radiology. 1976 Jun;119(3):559-68 - PubMed
  6. Joint Bone Spine. 2007 Jul;74(4):338-45 - PubMed
  7. Rev Rhum Mal Osteoartic. 1991 Oct;58(9):577-84 - PubMed
  8. Curr Opin Rheumatol. 2001 Jul;13(4):280-4 - PubMed
  9. Ann Rheum Dis. 2007 Jan;66(1):92-8 - PubMed
  10. Rev Rhum Engl Ed. 1995 Jan;62(1):53-4 - PubMed
  11. BMC Musculoskelet Disord. 2007 Feb 27;8:20 - PubMed
  12. J Rheumatol. 1997 Feb;24(2):249-52 - PubMed
  13. Ann Rheum Dis. 1999 Nov;58(11):722-3 - PubMed
  14. JAMA. 1985 Nov 15;254(19):2763-7 - PubMed
  15. Arthritis Rheum. 2005 Jun 15;53(3):440-4 - PubMed
  16. Drugs Aging. 2009;26(4):273-93 - PubMed
  17. Rheumatol Int. 2007 Aug;27(10):927-33 - PubMed
  18. Rev Rhum Mal Osteoartic. 1983 Nov;50(11):733-43 - PubMed
  19. J Rheumatol. 1990 May;17(5):633-9 - PubMed
  20. Clin Exp Rheumatol. 2001 May-Jun;19(3):291-6 - PubMed
  21. Curr Opin Rheumatol. 2007 Jul;19(4):346-52 - PubMed
  22. Ann Rheum Dis. 1999 Apr;58(4):226-9 - PubMed
  23. Rheum Dis Clin North Am. 1998 Nov;24(4):753-70 - PubMed
  24. Ann Rheum Dis. 2005 Aug;64(8):1141-4 - PubMed
  25. Drugs Aging. 2010 Jul 1;27(7):523-31 - PubMed
  26. J Rheumatol. 1993 Feb;20(2):390-3 - PubMed
  27. Clin Rheumatol. 1997 Nov;16(6):614-6 - PubMed
  28. Arthritis Rheum. 1991 Oct;34(10):1218-27 - PubMed
  29. J Rheumatol. 2002 Jun;29(6):1121-3 - PubMed
  30. Ann Rheum Dis. 2009 Jun;68(6):777-83 - PubMed
  31. Best Pract Res Clin Rheumatol. 2006 Jun;20(3):401-17 - PubMed
  32. Drugs Aging. 2009;26(8):647-64 - PubMed
  33. Ann Rheum Dis. 1997 Mar;56(3):176-9 - PubMed
  34. Joint Bone Spine. 2000;67(6):544-9 - PubMed
  35. Ann Rheum Dis. 1995 Aug;54(8):681-4 - PubMed
  36. Arthritis Rheum. 1998 Jan;41(1):58-67 - PubMed
  37. Ann Rheum Dis. 2007 Nov;66(11):1479-84 - PubMed
  38. J Rheumatol. 2007 Feb;34(2):259-65 - PubMed
  39. J Rheumatol. 1989 Sep;16(9):1214-7 - PubMed
  40. Rev Rhum Mal Osteoartic. 1990 Feb;57(2):85-9 - PubMed
  41. J Rheumatol. 1999 Dec;26(12):2622-7 - PubMed
  42. Arthritis Res Ther. 2006;8(5):R143 - PubMed
  43. Rev Rhum Mal Osteoartic. 1992 Sep;59(6 Pt 2):37S-42S - PubMed
  44. Joint Bone Spine. 2000;67(5):475-7 - PubMed
  45. J Rheumatol. 1993 Jan;20(1):205-6 - PubMed
  46. J Rheumatol. 2007 Jan;34(1):5-7 - PubMed
  47. J Rheumatol. 2007 Jan;34(1):110-6 - PubMed

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