Display options
Cite
Mulder CK, Gerkema MP, Van der Zee EA. Circadian clocks and memory: time-place learning. Front Mol Neurosci. 2013;6:8doi: 10.3389/fnmol.2013.00008.
Mulder, C. K., Gerkema, M. P., & Van der Zee, E. A. (2013). Circadian clocks and memory: time-place learning. Frontiers in molecular neuroscience, 68. https://doi.org/10.3389/fnmol.2013.00008
Mulder, C K, et al. "Circadian clocks and memory: time-place learning." Frontiers in molecular neuroscience vol. 6 (2013): 8. doi: https://doi.org/10.3389/fnmol.2013.00008
Mulder CK, Gerkema MP, Van der Zee EA. Circadian clocks and memory: time-place learning. Front Mol Neurosci. 2013 Apr 11;6:8. doi: 10.3389/fnmol.2013.00008. eCollection 2013. PMID: 23596390; PMCID: PMC3622895.
Copy Download .nbib Format: NLM
Share it on

Front Mol Neurosci. 2013 Apr 11;6:8. doi: 10.3389/fnmol.2013.00008. eCollection 2013.

Circadian clocks and memory: time-place learning.

Frontiers in molecular neuroscience

C K Mulder, M P Gerkema, E A Van der Zee

Affiliations

  1. Department of Molecular Neurobiology, University of Groningen Groningen, Netherlands ; Department of Chronobiology, University of Groningen Groningen, Netherlands.

PMID: 23596390 PMCID: PMC3622895 DOI: 10.3389/fnmol.2013.00008

Abstract

Time-Place learning (TPL) refers to the ability of animals to remember important events that vary in both time and place. This ability is thought to be functional to optimize resource localization and predator avoidance in a circadian changing environment. Various studies have indicated that animals use their circadian system for TPL. However, not much is known about this specific role of the circadian system in cognition. This review aims to put TPL in a broader context and to provide an overview of historical background, functional aspects, and future perspectives of TPL. Recent advances have increased our knowledge on establishing TPL in a laboratory setting, leading to the development of a behavioral paradigm demonstrating the circadian nature of TPL in mice. This has enabled the investigation of circadian clock components on a functional behavioral level. Circadian TPL (cTPL) was found to be Cry clock gene dependent, confirming the essential role of Cry genes in circadian rhythms. In contrast, preliminary results have shown that cTPL is independent of Per genes. Circadian system decline with aging predicts that cTPL is age sensitive, potentially qualifying TPL as a functional model for episodic memory and aging. The underlying neurobiological mechanism of TPL awaits further examination. Here we discuss some putative mechanisms.

Keywords: Cry; aging; circadian; clock genes; learning; memory; place; time

References

  1. ASN Neuro. 2009 Jun 10;1(3): - PubMed
  2. Neurobiol Learn Mem. 2005 Nov;84(3):214-21 - PubMed
  3. Brain Res Bull. 2008 May 15;76(1-2):141-51 - PubMed
  4. J Biol Rhythms. 2011 Aug;26(4):305-13 - PubMed
  5. Front Integr Neurosci. 2011 Aug 11;5:36 - PubMed
  6. Science. 2009 Sep 25;325(5948):1700-4 - PubMed
  7. Brain Res. 1991 Mar 1;542(2):348-52 - PubMed
  8. Behav Brain Res. 2000 Sep;114(1-2):221-33 - PubMed
  9. Cell. 2008 Jul 25;134(2):317-28 - PubMed
  10. Proc Natl Acad Sci U S A. 1958 Sep 15;44(9):965-73 - PubMed
  11. Learn Behav. 2007 Feb;35(1):71-8 - PubMed
  12. Behav Brain Res. 2011 Aug 10;221(2):466-80 - PubMed
  13. Behav Brain Res. 2002 Aug 21;134(1-2):283-90 - PubMed
  14. Eur J Neurosci. 2009 Nov;30(9):1756-66 - PubMed
  15. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):16058-63 - PubMed
  16. Neuron. 2011 Aug 25;71(4):571-3 - PubMed
  17. J Biol Rhythms. 2002 Aug;17(4):330-44 - PubMed
  18. Behav Processes. 2003 Jun 30;63(2):95-110 - PubMed
  19. Behav Biol. 1975 Jun;14(2):135-49 - PubMed
  20. Brain Res Bull. 1991 Sep-Oct;27(3-4):441-5 - PubMed
  21. Neurosci Biobehav Rev. 1980 Summer;4(2):119-31 - PubMed
  22. J Circadian Rhythms. 2008 Mar 20;6:5 - PubMed
  23. Behav Brain Res. 2002 Jun 15;133(1):95-108 - PubMed
  24. J Exp Anal Behav. 1999 Mar;71(2):215-51 - PubMed
  25. J Biol Rhythms. 2002 Aug;17(4):284-92 - PubMed
  26. Hippocampus. 2010 Mar;20(3):377-88 - PubMed
  27. Ann N Y Acad Sci. 1984;423:488-514 - PubMed
  28. Oecologia. 1981 Sep;50(3):391-406 - PubMed
  29. Experientia. 1950 Jun 15;6(6):210-21 - PubMed
  30. Neurobiol Learn Mem. 2008 May;89(4):604-7 - PubMed
  31. Anim Learn Behav. 2002 Nov;30(4):387-93 - PubMed
  32. Neurobiol Learn Mem. 2004 May;81(3):217-20 - PubMed
  33. Chronobiol Int. 2009 Oct;26(7):1273-89 - PubMed
  34. J Neurosci. 2011 Jul 20;31(29):10640-7 - PubMed
  35. Physiol Behav. 1985 Jun;34(6):883-7 - PubMed
  36. Behav Processes. 1996 Oct;38(1):77-88 - PubMed
  37. J Neurosci. 2009 Oct 14;29(41):12824-30 - PubMed
  38. Learn Behav. 2006 May;34(2):131-43 - PubMed
  39. Am J Physiol Regul Integr Comp Physiol. 2006 Jun;290(6):R1524-6 - PubMed
  40. Nat Rev Neurosci. 2012 Mar 07;13(5):325-35 - PubMed
  41. J Biol Chem. 2002 Aug 16;277(33):29519-25 - PubMed
  42. Behav Processes. 1996 Jun;36(3):253-62 - PubMed
  43. Behav Processes. 2004 Nov 30;67(3):533-7 - PubMed
  44. Chronobiol Int. 2000 Nov;17(6):719-32 - PubMed
  45. Behav Processes. 2002 Jun 28;58(3):157-166 - PubMed
  46. Neurosci Lett. 2003 Sep 18;348(3):131-4 - PubMed
  47. Neurobiol Learn Mem. 2001 Jan;75(1):51-62 - PubMed
  48. J Exp Biol. 2000 Aug;203(Pt 15):2341-8 - PubMed
  49. Sleep. 2010 Nov;33(11):1465-73 - PubMed
  50. Neurobiol Learn Mem. 2008 May;89(4):591-4 - PubMed
  51. Behav Brain Res. 2011 Aug 10;221(2):412-23 - PubMed
  52. Nature. 1985 Feb 21-27;313(6004):678-9 - PubMed
  53. Behav Processes. 2004 Sep 30;67(2):183-93 - PubMed
  54. Brain Res. 1999 Jan 23;816(2):572-9 - PubMed
  55. Brain Res. 1996 Nov 11;739(1-2):12-8 - PubMed
  56. Cold Spring Harb Symp Quant Biol. 1960;25:379-87 - PubMed
  57. Nat Neurosci. 1998 Dec;1(8):693-700 - PubMed
  58. Curr Biol. 2008 Jun 3;18(11):844-8 - PubMed
  59. Physiol Behav. 2004 Sep 15;82(2-3):339-44 - PubMed
  60. Behav Brain Res. 2004 Apr 2;150(1-2):201-5 - PubMed
  61. J Comp Physiol Psychol. 1957 Oct;50(5):457-60 - PubMed
  62. Behav Processes. 1999 Nov;48(1-2):35-48 - PubMed
  63. Behav Biol. 1973 Jul;9(1):1-14 - PubMed
  64. Nat Neurosci. 2008 Sep;11(9):1074-82 - PubMed
  65. Behav Brain Res. 2002 Oct 17;136(1):179-84 - PubMed
  66. Cognition. 1990 Nov;37(1-2):1-22 - PubMed
  67. Neurobiol Learn Mem. 2009 Jan;91(1):81-4 - PubMed
  68. Am J Physiol. 1984 Feb;246(2 Pt 2):R161-83 - PubMed
  69. Sci Am. 1974 Dec;231(6):96-7 - PubMed
  70. J Neural Transm (Vienna). 2006 Mar;113(3):347-56 - PubMed
  71. Science. 1973 Apr 15;180(4082):208-10 - PubMed
  72. Mol Cell Neurosci. 2008 Feb;37(2):209-21 - PubMed
  73. Behav Processes. 2000 Mar 31;49(1):21-33 - PubMed
  74. J Exp Psychol Anim Behav Process. 1997 Apr;23(2):232-47 - PubMed
  75. Annu Rev Physiol. 2010;72:517-49 - PubMed
  76. Nature. 1999 Jul 8;400(6740):169-73 - PubMed
  77. Acta Neurobiol Exp (Wars). 2004;64(3):303-17 - PubMed
  78. Brain Res Bull. 2003 Feb 15;59(6):467-72 - PubMed
  79. Behav Processes. 1999 Mar 1;44(3):287-99 - PubMed
  80. Biol Chem. 2003 May;384(5):729-36 - PubMed
  81. Neuron. 2011 Aug 25;71(4):737-49 - PubMed
  82. Nat Rev Neurosci. 2005 Oct;6(10):755-65 - PubMed
  83. Neuron. 2002 Feb 28;33(5):827-40 - PubMed
  84. J Biol Rhythms. 1989 Fall;4(3):305-25 - PubMed
  85. Brain Res Brain Res Protoc. 2005 Dec;16(1-3):10-9 - PubMed
  86. J Neurosci. 2006 Aug 23;26(34):8662-71 - PubMed
  87. J Biol Chem. 2002 Jan 4;277(1):267-71 - PubMed
  88. Physiol Behav. 1990 Oct;48(4):523-9 - PubMed
  89. Acta Psychiatr Belg. 1985 Sep-Oct;85(5):568-81 - PubMed
  90. Curr Opin Pulm Med. 2009 Nov;15(6):534-9 - PubMed

Publication Types