Display options
Share it on

Annu Rev Econom. 2012 Jul 01;4:627-662. doi: 10.1146/annurev-economics-080511-110939. Epub 2012 Jun 18.

The Promises and Pitfalls of Genoeconomics*.

Annual review of economics

Daniel J Benjamin, David Cesarini, Christopher F Chabris, Edward L Glaeser, David I Laibson, Vilmundur Guðnason, Tamara B Harris, Lenore J Launer, Shaun Purcell, Albert Vernon Smith, Magnus Johannesson, Patrik K E Magnusson, Jonathan P Beauchamp, Nicholas A Christakis, Craig S Atwood, Benjamin Hebert, Jeremy Freese, Robert M Hauser, Taissa S Hauser, Alexander Grankvist, Christina M Hultman, Paul Lichtenstein

Affiliations

  1. Department of Economics, Cornell University, Ithaca, New York 14853; National Bureau of Economic Research, Cambridge, Massachusetts 02138; [email protected].

PMID: 23482589 PMCID: PMC3592970 DOI: 10.1146/annurev-economics-080511-110939

Abstract

This article reviews existing research at the intersection of genetics and economics, presents some new findings that illustrate the state of genoeconomics research, and surveys the prospects of this emerging field. Twin studies suggest that economic outcomes and preferences, once corrected for measurement error, appear to be about as heritable as many medical conditions and personality traits. Consistent with this pattern, we present new evidence on the heritability of permanent income and wealth. Turning to genetic association studies, we survey the main ways that the direct measurement of genetic variation across individuals is likely to contribute to economics, and we outline the challenges that have slowed progress in making these contributions. The most urgent problem facing researchers in this field is that most existing efforts to find associations between genetic variation and economic behavior are based on samples that are too small to ensure adequate statistical power. This has led to many false positives in the literature. We suggest a number of possible strategies to improve and remedy this problem: (

Keywords: GWAS; genetics; heritability

References

  1. PLoS One. 2011;6(5):e19382 - PubMed
  2. Circ Cardiovasc Genet. 2009 Feb;2(1):73-80 - PubMed
  3. Am J Epidemiol. 2007 May 1;165(9):1076-87 - PubMed
  4. PLoS One. 2011;6(6):e20128 - PubMed
  5. Eur J Neurosci. 2002 Aug;16(3):399-402 - PubMed
  6. Twin Res. 2003 Oct;6(5):399-408 - PubMed
  7. N Engl J Med. 2008 Dec 11;359(24):2558-66 - PubMed
  8. Am Econ Rev. 2016 Jun;106(6):1562-5 - PubMed
  9. Science. 2007 May 11;316(5826):889-94 - PubMed
  10. Transl Psychiatry. 2012 Apr 17;2:e102 - PubMed
  11. PLoS Genet. 2009 Jun;5(6):e1000505 - PubMed
  12. N Engl J Med. 2009 Apr 23;360(17):1699-701 - PubMed
  13. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8026-31 - PubMed
  14. Int J Epidemiol. 2003 Feb;32(1):1-22 - PubMed
  15. Science. 1994 Jun 17;264(5166):1733-9 - PubMed
  16. Health Econ. 2011 Aug;20(8):884-8 - PubMed
  17. PLoS One. 2009;4(2):e4362 - PubMed
  18. J Health Econ. 2009 May;28(3):578-97 - PubMed
  19. PLoS One. 2009 Dec 31;4(12):e8516 - PubMed
  20. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2118-23 - PubMed
  21. Neuropsychol Rev. 2009 Dec;19(4):451-77 - PubMed
  22. Genes Brain Behav. 2005 Jul;4(5):289-301 - PubMed
  23. J Neurobiol. 2003 Jan;54(1):4-45 - PubMed
  24. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3721-6 - PubMed
  25. Nat Rev Genet. 2008 Apr;9(4):255-66 - PubMed
  26. Proc Biol Sci. 2009 Dec 7;276(1676):4181-8 - PubMed
  27. PLoS One. 2009 May 20;4(5):e5535 - PubMed
  28. J Neurosci Psychol Econ. 2012 Nov;5(4): - PubMed
  29. Mol Psychiatry. 2012 Mar;17(3):337-49 - PubMed
  30. Mol Psychiatry. 2011 Oct;16(10):996-1005 - PubMed
  31. Science. 1994 Sep 30;265(5181):2037-48 - PubMed
  32. Health Econ. 2008 Sep;17(9):1089-104 - PubMed
  33. Ann Hum Biol. 2006 Sep-Dec;33(5-6):593-603 - PubMed
  34. Nature. 2005 Jun 2;435(7042):673-6 - PubMed
  35. CNS Spectr. 2008 Jul;13(7):598-605 - PubMed
  36. J Labor Econ. 1986 Jul;4(3 Pt. 2):1-47 - PubMed
  37. PLoS Med. 2008 Mar 4;5(3):e52 - PubMed
  38. Biol Psychiatry. 2000 Feb 1;47(3):183-99 - PubMed
  39. Biodemography Soc Biol. 2009;55(2):238-51 - PubMed
  40. PLoS One. 2010 Nov 03;5(11):e13765 - PubMed
  41. Brain Res. 2006 May 23;1090(1):15-22 - PubMed
  42. J Intern Med. 2002 Sep;252(3):184-205 - PubMed
  43. Am Sociol Rev. 1980 Oct;45(5):723-36 - PubMed
  44. Behav Brain Funct. 2007 Jan 10;3:2 - PubMed
  45. Am J Psychiatry. 2011 Oct;168(10):1041-9 - PubMed
  46. Ann Hum Genet. 2008 Sep;72(Pt 5):630-5 - PubMed
  47. J Pers. 1996 Sep;64(3):577-91 - PubMed
  48. Ann N Y Acad Sci. 2011 Mar;1220:162-71 - PubMed
  49. Stat Med. 2008 Apr 15;27(8):1133-63 - PubMed
  50. PLoS One. 2010 Jun 16;5(6):e11153 - PubMed
  51. J Med Genet. 2007 May;44(5):289-97 - PubMed
  52. Psychol Sci. 2012;23(11):1314-23 - PubMed
  53. Soc Cogn Affect Neurosci. 2009 Dec;4(4):399-408 - PubMed
  54. Genes Brain Behav. 2008 Apr;7(3):266-75 - PubMed
  55. Proc Biol Sci. 2011 Jul 7;278(1714):2053-9 - PubMed
  56. Int J Epidemiol. 2012 Feb;41(1):273-86 - PubMed
  57. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15631-4 - PubMed
  58. Eur J Epidemiol. 2010;25(1):1-3 - PubMed
  59. J Hum Genet. 2011 Jun;56(6):456-9 - PubMed
  60. Science. 2001 Feb 16;291(5507):1304-51 - PubMed
  61. Behav Genet. 2012 Jan;42(1):1-2 - PubMed
  62. Nature. 2009 Aug 6;460(7256):748-52 - PubMed
  63. Neuron. 2010 Mar 25;65(6):831-44 - PubMed
  64. Nature. 2010 Oct 14;467(7317):832-8 - PubMed
  65. Bioinformatics. 2003 Jan;19(1):149-50 - PubMed
  66. J Polit Econ. 2010 Jul 1;121(1):1-27 - PubMed
  67. Nature. 2001 Feb 15;409(6822):860-921 - PubMed
  68. Psychol Methods. 2002 Mar;7(1):83-104 - PubMed
  69. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1977-81 - PubMed
  70. PLoS One. 2009 Aug 20;4(8):e6704 - PubMed
  71. Nat Genet. 2006 Aug;38(8):904-9 - PubMed
  72. Ann N Y Acad Sci. 2010 Nov;1212:59-77 - PubMed
  73. Twin Res Hum Genet. 2009 Feb;12(1):103-7 - PubMed
  74. Nat Genet. 2010 Jul;42(7):565-9 - PubMed
  75. J Econ Perspect. 2011 Fall;25(4):57-82 - PubMed
  76. Biol Psychiatry. 2008 Jul 15;64(2):137-44 - PubMed
  77. Mol Psychiatry. 2004 Jun;9(6):582-6 - PubMed

Publication Types

Grant support