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Nanda SK, Sarangi R, Ray L, et al. Factitious Biochemical Reports which are Caused Due to Paraproteinaemia in Multiple Myeloma - A Case Report. J Clin Diagn Res. 2012;7(2):350-2doi: 10.7860/JCDR/2013/5173.2765.
Nanda, S. K., Sarangi, R., Ray, L., Kumar, A., & Padhi, S. (2013). Factitious Biochemical Reports which are Caused Due to Paraproteinaemia in Multiple Myeloma - A Case Report. Journal of clinical and diagnostic research : JCDR, 7(2), 350-2. https://doi.org/10.7860/JCDR/2013/5173.2765
Nanda, Sunil Kumar, et al. "Factitious Biochemical Reports which are Caused Due to Paraproteinaemia in Multiple Myeloma - A Case Report." Journal of clinical and diagnostic research : JCDR vol. 7,2 (2013): 350-2. doi: https://doi.org/10.7860/JCDR/2013/5173.2765
Nanda SK, Sarangi R, Ray L, Kumar A, Padhi S. Factitious Biochemical Reports which are Caused Due to Paraproteinaemia in Multiple Myeloma - A Case Report. J Clin Diagn Res. 2013 Feb;7(2):350-2. doi: 10.7860/JCDR/2013/5173.2765. Epub 2012 Dec 24. PMID: 23542790; PMCID: PMC3592309.
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J Clin Diagn Res. 2013 Feb;7(2):350-2. doi: 10.7860/JCDR/2013/5173.2765. Epub 2012 Dec 24.

Factitious Biochemical Reports which are Caused Due to Paraproteinaemia in Multiple Myeloma - A Case Report.

Journal of clinical and diagnostic research : JCDR

Sunil Kumar Nanda, Rajlaxmi Sarangi, Lopamudra Ray, Anil Kumar, Somanath Padhi

Affiliations

  1. Associate Professor, Department of Biochemistry.

PMID: 23542790 PMCID: PMC3592309 DOI: 10.7860/JCDR/2013/5173.2765

Abstract

Factitious biochemical reports result in the misguiding of clinicians, unnecessary retesting, wrong diagnoses and incorrect treatments. A vigilant biochemist identifies these factitious biochemical reports and alerts the clinician regarding the proper interpretation of the biochemical reports, thus preventing a misdiagnosis and an incorrect treatment. We are presenting a case report of a multiple myeloma patient who presented with factitious biochemical reports which were caused due to paraproteinaemia. In the present case, the patient presented with an underestimation of urea and creatinine, an underestimation of sodium, low albumin levels and high phosphate levels. On repeating the same tests after dilutions and deproteinizing, the effects of the paraproteins on the above mentioned tests were reduced. Thus, from the observations of our study, we suggest that the interference by paraproteinaemia can be reduced by analyzing the biochemical parameters after dilution and deproteinization.

Keywords: Deproteinization; Multiple myeloma; Paraproteinemia

References

  1. Semin Oncol. 2003 Apr;30(2):110-5 - PubMed
  2. Arch Pathol Lab Med. 2003 Jan;127(1):55-9 - PubMed
  3. Acta Clin Belg. 2004 Sep-Oct;59(5):263-73 - PubMed
  4. Clin Chem. 2004 Sep;50(9):1691-3 - PubMed
  5. Transfusion. 2004 Jun;44(6):801 - PubMed
  6. Am J Clin Pathol. 2009 Feb;131(2):195-204 - PubMed
  7. Arch Pathol Lab Med. 2005 Apr;129(4):454-5 - PubMed
  8. Clin Chem. 2002 Jun;48(6 Pt 1):964 - PubMed
  9. Br J Haematol. 2003 Jun;121(5):749-57 - PubMed

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