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Rao U, Thakur PK, G NP, et al. Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola. Bioinformation. 2013;9(4):182-6doi: 10.6026/97320630009182.
Rao, U., Thakur, P. K., G, N. P., Banakar, P., & Kumar, M. (2013). Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola. Bioinformation, 9(4), 182-6. https://doi.org/10.6026/97320630009182
Rao, Uma, et al. "Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola." Bioinformation vol. 9,4 (2013): 182-6. doi: https://doi.org/10.6026/97320630009182
Rao U, Thakur PK, G NP, Banakar P, Kumar M. Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola. Bioinformation. 2013;9(4):182-6. doi: 10.6026/97320630009182. Epub 2013 Feb 21. PMID: 23520432; PMCID: PMC3602887.
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Bioinformation. 2013;9(4):182-6. doi: 10.6026/97320630009182. Epub 2013 Feb 21.

Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola.

Bioinformation

Uma Rao, Prasoon Kumar Thakur, Nagavara Prasad G, Prakash Banakar, Mukesh Kumar

Affiliations

  1. Division of Nematology, Indian Agricultural Research Institute (IARI), New Delhi - 110012.

PMID: 23520432 PMCID: PMC3602887 DOI: 10.6026/97320630009182

Abstract

Root-knot nematodes (RKNs), Meloidogyne spp, are found in all temperate and tropical areas, and are among the most damaging plant pathogens worldwide. M. graminincola is an economically important root parasite on upland, lowland and deepwater rice. FMRFamide-like peptides (FLPs) play significant role as neurotransmitters or neuromodulators in the nervous system and proposed as one of the important targets for the plant parasitic nematode management. Therefore, for the first time, we have cloned and characterized two neuropeptide genes (flp-1 and flp-12) from the cDNA of preparasitic second stage juveniles of M. graminicola. The flp-12 contains putative 22 residue long signal peptide at N-terminal suggesting function as an extra-cellular protein. We have found highly conserved motif LFRGR in flp-1. These two flp genes could be interesting and potential targets for functional validation to explore their utility for designing management strategies.

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