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Kim YG, Kim HJ, Choi WS, et al. Does a negative ergonovine provocation test truly predict freedom from variant angina?. Korean Circ J. 2013;43(3):199-203doi: 10.4070/kcj.2013.43.3.199.
Kim, Y. G., Kim, H. J., Choi, W. S., Im, M. S., Yoon, C. H., Suh, J. W., & Choi, D. J. (2013). Does a negative ergonovine provocation test truly predict freedom from variant angina?. Korean circulation journal, 43(3), 199-203. https://doi.org/10.4070/kcj.2013.43.3.199
Kim, Yun Gi, et al. "Does a negative ergonovine provocation test truly predict freedom from variant angina?." Korean circulation journal vol. 43,3 (2013): 199-203. doi: https://doi.org/10.4070/kcj.2013.43.3.199
Kim YG, Kim HJ, Choi WS, Im MS, Yoon CH, Suh JW, Choi DJ. Does a negative ergonovine provocation test truly predict freedom from variant angina?. Korean Circ J. 2013 Mar;43(3):199-203. doi: 10.4070/kcj.2013.43.3.199. Epub 2013 Mar 31. PMID: 23613700; PMCID: PMC3629249.
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Korean Circ J. 2013 Mar;43(3):199-203. doi: 10.4070/kcj.2013.43.3.199. Epub 2013 Mar 31.

Does a negative ergonovine provocation test truly predict freedom from variant angina?.

Korean circulation journal

Yun Gi Kim, Hyun Jin Kim, Won-Suk Choi, Moon-Sun Im, Chang-Hwan Yoon, Jung-Won Suh, Dong-Ju Choi

Affiliations

  1. Cardiovascular Center and Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

PMID: 23613700 PMCID: PMC3629249 DOI: 10.4070/kcj.2013.43.3.199

Abstract

Ergonovine provocation test is known to be very sensitive for diagnosing variant angina. The patient described in this study initially presented with atypical chest pain and underwent coronary angiography and ergonovine provocation tests, which were negative. The patient was subsequently prescribed a proton pump inhibitor and prokinetics for pain relief, but then presented with acute myocardial infarction and cardiogenic shock due to coronary artery vasospasm 5 years later. This case suggests that ergonovine provocation test generates false negative results, which can lead to unwanted outcomes. Even with a negative ergonovine provocation test, prescription of calcium channel blockers or nitrates should be considered in patients with a clinical history suggestive of variant angina.

Keywords: Angina pectoris, variant; Coronary vasospasm; Ergonovine

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