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Saigal S, Singh RK, Poddar B. Acute methotrexate toxicity presenting as multiorgan failure and acute pneumonitis: A rare case report. Indian J Crit Care Med. 2012;16(4):225-7doi: 10.4103/0972-5229.106509.
Saigal, S., Singh, R. K., & Poddar, B. (2012). Acute methotrexate toxicity presenting as multiorgan failure and acute pneumonitis: A rare case report. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 16(4), 225-7. https://doi.org/10.4103/0972-5229.106509
Saigal, Saurabh, et al. "Acute methotrexate toxicity presenting as multiorgan failure and acute pneumonitis: A rare case report." Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine vol. 16,4 (2012): 225-7. doi: https://doi.org/10.4103/0972-5229.106509
Saigal S, Singh RK, Poddar B. Acute methotrexate toxicity presenting as multiorgan failure and acute pneumonitis: A rare case report. Indian J Crit Care Med. 2012 Oct;16(4):225-7. doi: 10.4103/0972-5229.106509. PMID: 23559734; PMCID: PMC3610459.
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Indian J Crit Care Med. 2012 Oct;16(4):225-7. doi: 10.4103/0972-5229.106509.

Acute methotrexate toxicity presenting as multiorgan failure and acute pneumonitis: A rare case report.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

Saurabh Saigal, Ratender K Singh, Banani Poddar

Affiliations

  1. Department of Critical Care Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

PMID: 23559734 PMCID: PMC3610459 DOI: 10.4103/0972-5229.106509

Abstract

Acute methotrexate toxicity rarely presents as medical emergency in form of multiorgan failure. Acute pneumonitis following low-dose methotrexate is rarely reported in literature. It is important to recognize this, as the drug must be discontinued immediately and rescue measures in form of folinic acid and hydration instituted promptly.

Keywords: Folinic acid; methotrexate; pneumonitis

References

  1. Ann Rheum Dis. 1988 Sep;47(9):784-8 - PubMed
  2. J Rheumatol. 1987 Dec;14(6):1164-71 - PubMed
  3. Ann Acad Med Singap. 2011 Feb;40(2):97-9 - PubMed
  4. Rheumatology (Oxford). 2004 Feb;43(2):143-7 - PubMed
  5. Br J Haematol. 2009 Sep;146(5):489-503 - PubMed
  6. Cancer. 1976 Feb;37(2 Suppl):1048-57 - PubMed
  7. Arthritis Rheum. 1997 Oct;40(10):1829-37 - PubMed
  8. Am J Obstet Gynecol. 1997 Mar;176(3):714-5 - PubMed
  9. Rheumatology (Oxford). 2008 Nov;47(11):1647-50 - PubMed

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