Display options
Cite
Coskun Benlidayi I, Guzel R. Oral bisphosphonate related osteonecrosis of the jaw: a challenging adverse effect. ISRN Rheumatol. 2013;2013:215034doi: 10.1155/2013/215034.
Coskun Benlidayi, I., & Guzel, R. (2013). Oral bisphosphonate related osteonecrosis of the jaw: a challenging adverse effect. ISRN rheumatology, 2013215034. https://doi.org/10.1155/2013/215034
Coskun Benlidayi, Ilke, and Guzel, Rengin. "Oral bisphosphonate related osteonecrosis of the jaw: a challenging adverse effect." ISRN rheumatology vol. 2013 (2013): 215034. doi: https://doi.org/10.1155/2013/215034
Coskun Benlidayi I, Guzel R. Oral bisphosphonate related osteonecrosis of the jaw: a challenging adverse effect. ISRN Rheumatol. 2013 May 16;2013:215034. doi: 10.1155/2013/215034. Print 2013. PMID: 23762600; PMCID: PMC3671545.
Copy Download .nbib Format: NLM
Share it on

ISRN Rheumatol. 2013 May 16;2013:215034. doi: 10.1155/2013/215034. Print 2013.

Oral bisphosphonate related osteonecrosis of the jaw: a challenging adverse effect.

ISRN rheumatology

Ilke Coskun Benlidayi, Rengin Guzel

Affiliations

  1. Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Cukurova University, Adana 01330, Turkey.

PMID: 23762600 PMCID: PMC3671545 DOI: 10.1155/2013/215034

Abstract

Oral bisphosphonates are the most commonly prescribed antiresorptive drugs for the treatment of osteoporosis. However, there are several adverse effects associated with oral bisphosphonates including the bisphosphonate related osteonecrosis of the jaw (BRONJ). With a better understanding of this side effect, reported incidences for BRONJ in oral bisphosphonate users have increased in time. The pathogenesis of BRONJ has not been well determined. Several risk factors such as dentoalveolar surgery, therapy duration, and concomitant steroid usage have been linked to BRONJ. Conservative and surgical methods can be preferred in the treatment. Preventative measures are of great importance for the patients at high risk. In this paper, osteonecrosis of the jaw secondary to oral bisphosphonates was reviewed in order to increase awareness as well as to renew the current knowledge.

References

  1. Joint Bone Spine. 2008 Jan;75(1):34-40 - PubMed
  2. Oncologist. 2009 Nov;14(11):1154-66 - PubMed
  3. Aust Endod J. 2009 Dec;35(3):119-30 - PubMed
  4. Clin Cases Miner Bone Metab. 2007 Jan;4(1):37-42 - PubMed
  5. Int J Oral Maxillofac Surg. 2013 Jan;42(1):149-50 - PubMed
  6. Am J Med. 2013 Jan;126(1):13-20 - PubMed
  7. J Oral Maxillofac Surg. 2012 Jul;70(7):1573-83 - PubMed
  8. J Craniomaxillofac Surg. 2011 Jun;39(4):272-7 - PubMed
  9. Int J Oral Maxillofac Surg. 2006 Jul;35(7):588-93 - PubMed
  10. J Oral Maxillofac Surg. 2009 Dec;67(12):2698-9 - PubMed
  11. J Oral Maxillofac Surg. 2012 Aug;70(8):1844-53 - PubMed
  12. Am J Med. 2008 Jun;121(6):475-483.e3 - PubMed
  13. J Oral Maxillofac Surg. 2007 Mar;65(3):415-23 - PubMed
  14. Surgeon. 2012 Feb;10(1):36-42 - PubMed
  15. ISRN Rheumatol. 2011;2011:654027 - PubMed
  16. Med Hypotheses. 2011 Nov;77(5):905-11 - PubMed
  17. J Am Dent Assoc. 2009 Jan;140(1):61-6 - PubMed
  18. Oral Oncol. 2006 Mar;42(3):327-9 - PubMed
  19. Osteoporos Int. 2010 May;21(5):847-53 - PubMed
  20. J Clin Oncol. 2003 Nov 15;21(22):4253-4 - PubMed
  21. J Oral Maxillofac Surg. 2007 Dec;65(12):2397-410 - PubMed
  22. J Am Dent Assoc. 2008 Dec;139(12):1674-7 - PubMed
  23. Med Oral Patol Oral Cir Bucal. 2012 Sep 01;17(5):e751-8 - PubMed
  24. Osteoporos Int. 2012 Nov;23(11):2721-5 - PubMed
  25. J Oral Maxillofac Surg. 2003 Sep;61(9):1115-7 - PubMed
  26. Hong Kong Med J. 2010 Apr;16(2):145-8 - PubMed
  27. J Med Case Rep. 2011 Sep 23;5:477 - PubMed
  28. Osteoporos Int. 2007 Oct;18(10):1363-70 - PubMed
  29. J Oral Maxillofac Surg. 2010 Sep;68(9):2241-7 - PubMed
  30. Bone. 2012 Nov;51(5):882-7 - PubMed
  31. J Am Dent Assoc. 2011 Nov;142(11):1243-51 - PubMed
  32. J Oral Maxillofac Surg. 2007 Mar;65(3):369-76 - PubMed
  33. Rom J Morphol Embryol. 2011;52(4):1233-41 - PubMed
  34. Oncologist. 2012;17(2):279-87 - PubMed
  35. Blood. 2008 Oct 1;112(7):2709-12 - PubMed
  36. Acta Medica (Hradec Kralove). 2012;55(3):111-5 - PubMed

Publication Types