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De Berardis D, Marini S, Piersanti M, et al. The Relationships between Cholesterol and Suicide: An Update. ISRN Psychiatry. 2012;2012:387901doi: 10.5402/2012/387901.
De Berardis, D., Marini, S., Piersanti, M., Cavuto, M., Perna, G., Valchera, A., Mazza, M., Fornaro, M., Iasevoli, F., Martinotti, G., & Di Giannantonio, M. (2012). The Relationships between Cholesterol and Suicide: An Update. ISRN psychiatry, 2012387901. https://doi.org/10.5402/2012/387901
De Berardis, Domenico, et al. "The Relationships between Cholesterol and Suicide: An Update." ISRN psychiatry vol. 2012 (2012): 387901. doi: https://doi.org/10.5402/2012/387901
De Berardis D, Marini S, Piersanti M, Cavuto M, Perna G, Valchera A, Mazza M, Fornaro M, Iasevoli F, Martinotti G, Di Giannantonio M. The Relationships between Cholesterol and Suicide: An Update. ISRN Psychiatry. 2012 Dec 23;2012:387901. doi: 10.5402/2012/387901. Print 2012. PMID: 23762765; PMCID: PMC3671696.
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ISRN Psychiatry. 2012 Dec 23;2012:387901. doi: 10.5402/2012/387901. Print 2012.

The Relationships between Cholesterol and Suicide: An Update.

ISRN psychiatry

Domenico De Berardis, Stefano Marini, Monica Piersanti, Marilde Cavuto, Giampaolo Perna, Alessandro Valchera, Monica Mazza, Michele Fornaro, Felice Iasevoli, Giovanni Martinotti, Massimo Di Giannantonio

Affiliations

  1. Psychiatric Service of Diagnosis and Treatment, Department of Mental Health, "G. Mazzini" Hospital, NHS, ASL 4, 64100 Teramo, Italy ; Department of Neurosciences and Imaging, "G. D'Annunzio" University, 66013 Chieti, Italy.

PMID: 23762765 PMCID: PMC3671696 DOI: 10.5402/2012/387901

Abstract

Cholesterol is a core component of the central nervous system, essential for the cell membrane stability and the correct functioning of neurotransmission. It has been observed that cholesterol may be somewhat associated with suicidal behaviours. Therefore, the aim of this paper was to elucidate current facts and views about the role of cholesterol levels in mood disorders. The majority of the studies reviewed in the present paper suggest an interesting relationship between cholesterol (especially lower levels) and suicidality. On the other hand, particularly during the last years, relationships between serum cholesterol and suicidality were doubted on the basis of some recent studies that have not found any correlation. However, the debate on relationships between cholesterol and suicide is open and longitudinal studies on a larger sample of patients are needed to further clarify this important issue.

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