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Hong CW, Libutti SK, Wood BJ. Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma. Curr Oncol. 2013;20(3):e274-7doi: 10.3747/co.20.1266.
Hong, C. W., Libutti, S. K., & Wood, B. J. (2013). Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma. Current oncology (Toronto, Ont.), 20(3), e274-7. https://doi.org/10.3747/co.20.1266
Hong, C W, et al. "Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma." Current oncology (Toronto, Ont.) vol. 20,3 (2013): e274-7. doi: https://doi.org/10.3747/co.20.1266
Hong CW, Libutti SK, Wood BJ. Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma. Curr Oncol. 2013 Jun;20(3):e274-7. doi: 10.3747/co.20.1266. PMID: 23737698; PMCID: PMC3671035.
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Curr Oncol. 2013 Jun;20(3):e274-7. doi: 10.3747/co.20.1266.

Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma.

Current oncology (Toronto, Ont.)

C W Hong, S K Libutti, B J Wood

Affiliations

  1. Center for Interventional Oncology, Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, U.S.A. ; Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, U.S.A.

PMID: 23737698 PMCID: PMC3671035 DOI: 10.3747/co.20.1266

Abstract

Radiofrequency ablation (rfa) is a standard treatment for small, unresectable hepatocellular carcinomas (hccs). However, rfa for larger tumours is less successful, and intravenous lyso-thermosensitive liposomal doxorubicin during rfa is one technique postulated to potentially address that limitation. This drug-plus-device combination therapy was used to completely treat a hcc in a patient who underwent liver transplantation 79 days later.

Keywords: ablation; doxorubicin; hepatocellular carcinoma; liposomes; rfa

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