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Tetta C, Consiglio AL, Bruno S, et al. The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?. Muscles Ligaments Tendons J. 2012;2(3):212-21
Tetta, C., Consiglio, A. L., Bruno, S., Tetta, E., Gatti, E., Dobreva, M., Cremonesi, F., & Camussi, G. (2012). The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?. Muscles, ligaments and tendons journal, 2(3), 212-21.
Tetta, Ciro, et al. "The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?." Muscles, ligaments and tendons journal vol. 2,3 (2012): 212-21.
Tetta C, Consiglio AL, Bruno S, Tetta E, Gatti E, Dobreva M, Cremonesi F, Camussi G. The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?. Muscles Ligaments Tendons J. 2012 Oct 16;2(3):212-21. Print 2012 Jul. PMID: 23738299; PMCID: PMC3666529.
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Muscles Ligaments Tendons J. 2012 Oct 16;2(3):212-21. Print 2012 Jul.

The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?.

Muscles, ligaments and tendons journal

Ciro Tetta, Anna Lange Consiglio, Stefania Bruno, Emanuele Tetta, Emanuele Gatti, Miryana Dobreva, Fausto Cremonesi, Giovanni Camussi

Affiliations

  1. Center of Translational Regenerative Medicine, Fresenius Medical Care Deutschland GmbH, Torino, Italy.

PMID: 23738299 PMCID: PMC3666529

Abstract

Tendon injuries represent even today a challenge as repair may be exceedingly slow and incomplete. Regenerative medicine and stem cell technology have shown to be of great promise. Here, we will review the current knowledge on the mechanisms of the regenerative potential of mesenchymal stem cells (MSCs) obtained from different sources (bone marrow, fat, cord blood, placenta). More specifically, we will devote attention to the current use of MSCs that have been used experimentally and in limited numbers of clinical cases for the surgical treatment of subchondral-bone cysts, bone-fracture repair and cartilage repair. Based on the recently emerging role in regenerative mechanisms of soluble factors and of extracellular vesicles, we will discuss the potential of non-cellular therapies in horse tendon injuries.

Keywords: horse tendinopathies; microvesicles; regenerative medicine; soluble factors; stem cells

References

  1. Hepatology. 2008 May;47(5):1634-43 - PubMed
  2. Arch Orthop Trauma Surg. 2007 Nov;127(9):815-21 - PubMed
  3. BMC Med. 2012 Aug 23;10:95 - PubMed
  4. Vet Surg. 2006 Apr;35(3):232-42 - PubMed
  5. Disabil Rehabil. 2008;30(20-22):1752-8 - PubMed
  6. Vet Res Commun. 2007 Aug;31 Suppl 1:281-3 - PubMed
  7. Cell Stem Cell. 2008 Feb 7;2(2):141-50 - PubMed
  8. Front Biosci (Landmark Ed). 2009 Jan 01;14:4598-605 - PubMed
  9. PLoS One. 2007 Sep 26;2(9):e941 - PubMed
  10. Am J Respir Cell Mol Biol. 2005 Aug;33(2):145-52 - PubMed
  11. PLoS One. 2010 Jul 27;5(7):e11803 - PubMed
  12. Vet Med Int. 2010;2010:250978 - PubMed
  13. J Clin Invest. 2005 Jul;115(7):1743-55 - PubMed
  14. Lancet. 2004 Jul 10-16;364(9429):149-55 - PubMed
  15. Trends Cell Biol. 2009 Feb;19(2):43-51 - PubMed
  16. Cytotherapy. 2011 Apr;13(4):419-30 - PubMed
  17. Equine Vet J. 2003 Jan;35(1):99-102 - PubMed
  18. Am J Vet Res. 2008 Jul;69(7):928-37 - PubMed
  19. Stem Cell Res. 2010 May;4(3):214-22 - PubMed
  20. Int J Mol Med. 2004 Dec;14(6):1035-41 - PubMed
  21. BMC Musculoskelet Disord. 2007 Feb 23;8:16 - PubMed
  22. Tissue Eng. 1999 Jun;5(3):267-77 - PubMed
  23. Trends Biotechnol. 2007 Sep;25(9):409-16 - PubMed
  24. Kidney Int. 2007 Aug;72(4):430-41 - PubMed
  25. Nature. 2010 Aug 12;466(7308):829-34 - PubMed
  26. Vitam Horm. 2011;87:291-320 - PubMed
  27. Blood. 2002 May 15;99(10):3838-43 - PubMed
  28. Matrix Biol. 1997 Nov;16(5):255-71 - PubMed
  29. Stem Cells Dev. 2012 Jan 20;21(2):273-83 - PubMed
  30. Exp Hematol. 2010 Mar;38(3):233-45 - PubMed
  31. Vet Res Commun. 2008 Sep;32 Suppl 1:S51-5 - PubMed
  32. Stem Cell Res Ther. 2011 Feb 23;2(1):9 - PubMed
  33. Kidney Int. 2010 Nov;78(9):838-48 - PubMed
  34. Vet Res Commun. 2009 Dec;33(8):811-21 - PubMed
  35. J Orthop Res. 2007 Jul;25(7):913-25 - PubMed
  36. Cell Prolif. 2011 Aug;44(4):330-42 - PubMed
  37. Cell Tissue Res. 2012 Jan 28;347(3):677-688 - PubMed
  38. J Hand Surg Am. 2007 May-Jun;32(5):597-605 - PubMed
  39. Res Vet Sci. 1980 May;28(3):302-10 - PubMed
  40. Tissue Eng. 2007 Jun;13(6):1219-26 - PubMed
  41. Tissue Eng. 2007 Dec;13(12):2949-55 - PubMed
  42. Osteoarthritis Cartilage. 2006 Dec;14(12):1214-26 - PubMed
  43. J Orthop Res. 2003 May;21(3):420-31 - PubMed
  44. Nephrol Dial Transplant. 2011 May;26(5):1474-83 - PubMed
  45. J Tissue Eng Regen Med. 2012 Aug;6(8):622-35 - PubMed
  46. J Immunol. 2004 Jan 15;172(2):1266-72 - PubMed
  47. J Orthop Res. 2002 Sep;20(5):910-9 - PubMed
  48. Clin Orthop Relat Res. 1995 Aug;(317):3-6 - PubMed
  49. Equine Vet J. 2008 Mar;40(2):178-81 - PubMed
  50. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11002-7 - PubMed
  51. J Orthop Res. 2008 Jan;26(1):1-9 - PubMed
  52. Stem Cells. 2007 Aug;25(8):2025-32 - PubMed
  53. J Cell Physiol. 2007 Mar;210(3):684-91 - PubMed
  54. Exp Cell Res. 2003 Jul 15;287(2):289-300 - PubMed
  55. Blood. 1999 Dec 1;94(11):3791-9 - PubMed
  56. Cell Transplant. 2010;19(6):667-79 - PubMed
  57. Equine Vet J. 2012 Jan;44(1):25-32 - PubMed
  58. Blood. 2005 Feb 15;105(4):1815-22 - PubMed
  59. J Am Soc Nephrol. 2007 Sep;18(9):2486-96 - PubMed
  60. Nat Med. 2007 Oct;13(10):1219-27 - PubMed
  61. PLoS One. 2012;7(3):e33115 - PubMed
  62. J Orthop Res. 1998 Jul;16(4):406-13 - PubMed
  63. Stem Cells Dev. 2009 Apr;18(3):521-9 - PubMed
  64. Braz J Med Biol Res. 2010 May;43(5):425-30 - PubMed
  65. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11474-9 - PubMed
  66. Vet Clin North Am Equine Pract. 2011 Aug;27(2):315-33 - PubMed
  67. J Bone Joint Surg Am. 2010 Aug 18;92(10):1927-37 - PubMed
  68. Vet Surg. 2007 Oct;36(7):613-22 - PubMed
  69. Vet Res Commun. 2008 Sep;32 Suppl 1:S33-8 - PubMed
  70. Tissue Eng. 2005 Jan-Feb;11(1-2):41-9 - PubMed
  71. Tissue Eng. 2006 Apr;12(4):775-88 - PubMed
  72. J Hand Surg Br. 2001 Aug;26(4):307-13 - PubMed
  73. Stem Cells Dev. 2007 Oct;16(5):719-31 - PubMed
  74. Stem Cell Rev. 2008 Sep;4(3):137-47 - PubMed
  75. Transplantation. 2003 Feb 15;75(3):389-97 - PubMed
  76. Rheumatology (Oxford). 2002 Apr;41(4):474-6 - PubMed
  77. Muscles Ligaments Tendons J. 2012 Feb 15;1(3):68-76 - PubMed
  78. J Am Soc Nephrol. 2009 May;20(5):1053-67 - PubMed
  79. J Am Soc Nephrol. 2004 Jul;15(7):1794-804 - PubMed
  80. J Biol Regul Homeost Agents. 2011 Apr-Jun;25(2 Suppl):S75-84 - PubMed
  81. Blood. 2007 Oct 1;110(7):2440-8 - PubMed
  82. J Cell Sci. 2006 Jun 1;119(Pt 11):2204-13 - PubMed
  83. J Cell Biochem. 2006 Aug 1;98(5):1076-84 - PubMed
  84. Theriogenology. 2010 Sep 1;74(4):516-24 - PubMed
  85. J Cell Sci. 2000 Apr;113 ( Pt 7):1161-6 - PubMed
  86. Blood. 2004 Jun 15;103(12):4619-21 - PubMed
  87. Stem Cells. 2008 Aug;26(8):2075-82 - PubMed
  88. Leukemia. 2006 Sep;20(9):1487-95 - PubMed
  89. J Orthop Res. 2009 Oct;27(10):1392-8 - PubMed

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