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O'Leary DJ, Nazarian J, Millodot M. Which neurotransmitters modulate corneal sensitivity?. Clin Exp Optom. 1986;69(3):108-11doi: 10.1111/j.1444-0938.1986.tb06799.x.
O'Leary, D. J., Nazarian, J., & Millodot, M. (1986). Which neurotransmitters modulate corneal sensitivity?. Clinical & experimental optometry, 69(3), 108-11. https://doi.org/10.1111/j.1444-0938.1986.tb06799.x
O'Leary, D J, et al. "Which neurotransmitters modulate corneal sensitivity?." Clinical & experimental optometry vol. 69,3 (1986): 108-11. doi: https://doi.org/10.1111/j.1444-0938.1986.tb06799.x
O'Leary DJ, Nazarian J, Millodot M. Which neurotransmitters modulate corneal sensitivity?. Clin Exp Optom. 1986 May;69(3):108-11. doi: 10.1111/j.1444-0938.1986.tb06799.x. PMID: 23714129.
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Clin Exp Optom. 1986 May;69(3):108-11. doi: 10.1111/j.1444-0938.1986.tb06799.x.

Which neurotransmitters modulate corneal sensitivity?.

Clinical & experimental optometry

D J O'Leary, J Nazarian, M Millodot

Affiliations

  1. Cornea and Contact Lens Research Unit, School of Optometry, University of New South Wales, Sydney, AustraliaLaboratory of Experimental Optometry, UWIST, Cardiff, UK.

PMID: 23714129 DOI: 10.1111/j.1444-0938.1986.tb06799.x

Abstract

Corneal sensitivity was assessed before and after applying atropine (0.5, 0.05, 0.005% w/v), pilocarpine (1.0, 0.1%), eserine (0.1, 0.01%) and potassium chloride (171mM). Atropine (0.5 - 0.005%) significantly depressed corneal sensitivity; parasympathomimetics, taken together, significantly increased sensitivity. Exposure to potassium chloride for 2 min had no effect on sensitivity, nor did it affect corneal sensation. These results are consistent with the hypothesis that epithelial acetylcholine is a neurotransmitter to the corneal nerves. We conclude, however, that the nerves may have only weak muscarinic properties.

1986 Optometrists Association Australia.

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