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Nandha R, Gupta A, Hashmi A. Cutaneous adverse drug reactions in a tertiary care teaching hospital: A North Indian perspective. Int J Appl Basic Med Res. 2011;1(1):50-3doi: 10.4103/2229-516X.81982.
Nandha, R., Gupta, A., & Hashmi, A. (2011). Cutaneous adverse drug reactions in a tertiary care teaching hospital: A North Indian perspective. International journal of applied & basic medical research, 1(1), 50-3. https://doi.org/10.4103/2229-516X.81982
Nandha, Ruchika, et al. "Cutaneous adverse drug reactions in a tertiary care teaching hospital: A North Indian perspective." International journal of applied & basic medical research vol. 1,1 (2011): 50-3. doi: https://doi.org/10.4103/2229-516X.81982
Nandha R, Gupta A, Hashmi A. Cutaneous adverse drug reactions in a tertiary care teaching hospital: A North Indian perspective. Int J Appl Basic Med Res. 2011 Jan;1(1):50-3. doi: 10.4103/2229-516X.81982. PMID: 23776774; PMCID: PMC3657944.
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Int J Appl Basic Med Res. 2011 Jan;1(1):50-3. doi: 10.4103/2229-516X.81982.

Cutaneous adverse drug reactions in a tertiary care teaching hospital: A North Indian perspective.

International journal of applied & basic medical research

Ruchika Nandha, Anita Gupta, Arif Hashmi

Affiliations

  1. Department of Pharmacology, Dr HSJ Institute of Dental Sciences, Chandigarh, India.

PMID: 23776774 PMCID: PMC3657944 DOI: 10.4103/2229-516X.81982

Abstract

BACKGROUND: Cutaneous manifestations of adverse drug reactions are a common occurrence and need to be differentiated from other causes of similar manifestations. Active search is essential for identification of these as patients may tend to downplay the causal association between drug use and the subsequent cutaneous manifestation.

PURPOSE: To study the incidence of Cutaneous Adverse Drug Reactions (CADRs) in a tertiary care teaching hospital in North India.

METHODS: A prospective, observational study was conducted over a period of 6 months; using self-reporting method for selection of cases. The CADRs were graded as definite, possible and probable.

RESULTS: During the study period, 91 cases of CADRs were observed. Maximum incidence of CADRs was seen with antimicrobials (48.30%), followed by nonsteroidal anti-inflammatory drugs (21.90%). Maculopapular rash was the most common cutaneous manifestation of ADRs (42.85%).

CONCLUSION: CADRs are a common occurrence and awareness about the same is essential for diagnosis and prevention.

Keywords: Cutaneous adverse drug reactions; drug rash; drug reaction; pharmacovigilance

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