Display options
Cite
Pillai P, Corrigan CJ, Ying S. Airway epithelium in atopic and nonatopic asthma: similarities and differences. ISRN Allergy. 2011;2011:195846doi: 10.5402/2011/195846.
Pillai, P., Corrigan, C. J., & Ying, S. (2011). Airway epithelium in atopic and nonatopic asthma: similarities and differences. ISRN allergy, 2011195846. https://doi.org/10.5402/2011/195846
Pillai, Prathap, et al. "Airway epithelium in atopic and nonatopic asthma: similarities and differences." ISRN allergy vol. 2011 (2011): 195846. doi: https://doi.org/10.5402/2011/195846
Pillai P, Corrigan CJ, Ying S. Airway epithelium in atopic and nonatopic asthma: similarities and differences. ISRN Allergy. 2011 Dec 29;2011:195846. doi: 10.5402/2011/195846. Print 2011. PMID: 23724224; PMCID: PMC3658807.
Copy Download .nbib Format: NLM
Share it on

ISRN Allergy. 2011 Dec 29;2011:195846. doi: 10.5402/2011/195846. Print 2011.

Airway epithelium in atopic and nonatopic asthma: similarities and differences.

ISRN allergy

Prathap Pillai, Chris J Corrigan, Sun Ying

Affiliations

  1. MRC and Asthma UK Centre for Allergic Mechanisms of Asthma, The Department of Asthma, Allergy and Respiratory Science, Tower Wing, Guy's Hospital, King's College London, London SE1 9RT, UK.

PMID: 23724224 PMCID: PMC3658807 DOI: 10.5402/2011/195846

Abstract

Asthma is an inflammatory disorder of the airways, and the airway epithelium has the central role in its pathogenesis. In general, the airway inflammation is characterised by the infiltration of the epithelium and submucosa by a range of inflammatory cells driven largely by Th-2 lymphocytes, eosinophils, and mast cells. The pathogenic mechanisms of nonatopic asthma in comparison to its atopic counterpart have always been a subject of debate. Although clinically are two distinct entities, more similarities than differences have been observed between the two in terms of immunopathogenesis, underlying IgE mechanisms, and so on. in a number of previous studies. More information has become available in recent years comparing the ultrastructure of the epithelium in these two types of asthma. A comparison of airway epithelium in atopic and nonatopic asthma is presented here from the available information in the literature. Similarities outnumber the differences, until we unravel the mystery surrounding these two important phenotypes of asthma in more detail.

References

  1. Respir Med. 2005 Apr;99(4):429-43 - PubMed
  2. Allergy Asthma Proc. 2006 Sep-Oct;27(5):341-6 - PubMed
  3. Am J Respir Cell Mol Biol. 1997 Jan;16(1):1-8 - PubMed
  4. J Allergy Clin Immunol. 2006 Mar;117(3):688-95 - PubMed
  5. Am J Respir Crit Care Med. 1996 Nov;154(5):1497-504 - PubMed
  6. J Immunol. 1999 Dec 1;163(11):6321-9 - PubMed
  7. Am J Respir Crit Care Med. 2001 Feb;163(2):517-23 - PubMed
  8. J Allergy Clin Immunol. 1982 Sep;70(3):170-7 - PubMed
  9. Chem Immunol Allergy. 2007;93:106-136 - PubMed
  10. Am J Respir Crit Care Med. 1998 Nov;158(5 Pt 3):S141-5 - PubMed
  11. Thorax. 1988 Feb;43(2):98-102 - PubMed
  12. Curr Opin Allergy Clin Immunol. 2002 Feb;2(1):27-9 - PubMed
  13. Am J Respir Crit Care Med. 2002 Dec 15;166(12 Pt 1):1590-5 - PubMed
  14. J Allergy Clin Immunol. 2000 Oct;106(4):697-704 - PubMed
  15. J Allergy Clin Immunol. 1997 May;99(5):666-72 - PubMed
  16. Respir Med. 2010 Oct;104(10):1436-43 - PubMed
  17. Eur Respir J. 1997 Sep;10(9):2097-104 - PubMed
  18. J Allergy Clin Immunol. 2007 Jan;119(1):213-8 - PubMed
  19. Clin Exp Immunol. 1998 Nov;114(2):137-46 - PubMed
  20. Respir Med. 2005 Mar;99(3):347-54 - PubMed
  21. J Appl Physiol (1985). 2001 Sep;91(3):1035-40 - PubMed
  22. J Allergy Clin Immunol. 2007 Dec;120(6):1233-44; quiz 1245-6 - PubMed
  23. Immunol Today. 1999 Nov;20(11):528-33 - PubMed
  24. Respirology. 2003 Dec;8(4):432-46 - PubMed
  25. Am J Respir Crit Care Med. 2000 Dec;162(6):2295-301 - PubMed
  26. Am J Med. 1947 Nov;3(5):601-6 - PubMed
  27. Am Rev Respir Dis. 1992 Aug;146(2):500-6 - PubMed
  28. Am J Respir Crit Care Med. 2000 Jan;161(1):64-72 - PubMed
  29. Curr Opin Allergy Clin Immunol. 2004 Feb;4(1):53-6 - PubMed
  30. Int Rev Cytol. 1999;185:237-302 - PubMed
  31. Chest. 1992 Mar;101(3 Suppl):27S-29S - PubMed
  32. J Allergy Clin Immunol. 2004 Apr;113(4):756-63 - PubMed
  33. Int Arch Allergy Immunol. 1995 Feb;106(2):149-56 - PubMed
  34. J Allergy Clin Immunol. 1993 Jun;91(6):1198-205 - PubMed
  35. Am Rev Respir Dis. 1992 Jul;146(1):109-15 - PubMed
  36. Eur Respir J. 1996 Dec;9(12):2454-60 - PubMed
  37. Respir Med. 2007 Dec;101(12):2526-33 - PubMed
  38. Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):737-43 - PubMed
  39. J Immunol. 2005 Jun 15;174(12):8183-90 - PubMed
  40. J Clin Invest. 2001 Jun;107(11):1357-64 - PubMed
  41. Nat Rev Mol Cell Biol. 2000 Dec;1(3):208-16 - PubMed
  42. Am J Respir Crit Care Med. 1996 Jun;153(6 Pt 1):1931-7 - PubMed
  43. J Investig Allergol Clin Immunol. 1994 Sep-Oct;4(5):222-32 - PubMed
  44. Thorax. 2002 Apr;57(4):309-16 - PubMed

Publication Types