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Mould DR, Upton RN. Basic concepts in population modeling, simulation, and model-based drug development. CPT Pharmacometrics Syst Pharmacol. 2012;1:e6doi: 10.1038/psp.2012.4.
Mould, D. R., & Upton, R. N. (2012). Basic concepts in population modeling, simulation, and model-based drug development. CPT: pharmacometrics & systems pharmacology, 1e6. https://doi.org/10.1038/psp.2012.4
Mould, D R, and Upton, R N. "Basic concepts in population modeling, simulation, and model-based drug development." CPT: pharmacometrics & systems pharmacology vol. 1 (2012): e6. doi: https://doi.org/10.1038/psp.2012.4
Mould DR, Upton RN. Basic concepts in population modeling, simulation, and model-based drug development. CPT Pharmacometrics Syst Pharmacol. 2012 Sep 26;1:e6. doi: 10.1038/psp.2012.4. PMID: 23835886; PMCID: PMC3606044.
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CPT Pharmacometrics Syst Pharmacol. 2012 Sep 26;1:e6. doi: 10.1038/psp.2012.4.

Basic concepts in population modeling, simulation, and model-based drug development.

CPT: pharmacometrics & systems pharmacology

D R Mould, R N Upton

Affiliations

  1. Projections Research, Phoenixville, Pennsylvania, USA.

PMID: 23835886 PMCID: PMC3606044 DOI: 10.1038/psp.2012.4

Abstract

Modeling is an important tool in drug development; population modeling is a complex process requiring robust underlying procedures for ensuring clean data, appropriate computing platforms, adequate resources, and effective communication. Although requiring an investment in resources, it can save time and money by providing a platform for integrating all information gathered on new therapeutic agents. This article provides a brief overview of aspects of modeling and simulation as applied to many areas in drug development.CPT: Pharmacometrics & Systems Pharmacology (2012) 1, e6; doi:10.1038/psp.2012.4; advance online publication 26 September 2012.

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