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Saeteng S, Tantraworasin A, Siwachat S, et al. Preoperative plasmapheresis for elective thymectomy in myasthenia patient: is it necessary?. ISRN Neurol. 2013;2013:238783doi: 10.1155/2013/238783.
Saeteng, S., Tantraworasin, A., Siwachat, S., Lertprasertsuke, N., Euathrongchit, J., & Wannasopha, Y. (2013). Preoperative plasmapheresis for elective thymectomy in myasthenia patient: is it necessary?. ISRN neurology, 2013238783. https://doi.org/10.1155/2013/238783
Saeteng, Somcharoen, et al. "Preoperative plasmapheresis for elective thymectomy in myasthenia patient: is it necessary?." ISRN neurology vol. 2013 (2013): 238783. doi: https://doi.org/10.1155/2013/238783
Saeteng S, Tantraworasin A, Siwachat S, Lertprasertsuke N, Euathrongchit J, Wannasopha Y. Preoperative plasmapheresis for elective thymectomy in myasthenia patient: is it necessary?. ISRN Neurol. 2013 Jun 11;2013:238783. doi: 10.1155/2013/238783. Print 2013. PMID: 23840964; PMCID: PMC3693175.
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ISRN Neurol. 2013 Jun 11;2013:238783. doi: 10.1155/2013/238783. Print 2013.

Preoperative plasmapheresis for elective thymectomy in myasthenia patient: is it necessary?.

ISRN neurology

Somcharoen Saeteng, Apichat Tantraworasin, Sophon Siwachat, Nirush Lertprasertsuke, Juntima Euathrongchit, Yuttaphan Wannasopha

Affiliations

  1. General Thoracic Unit, Department of Surgery, Faculty of Medicine, Chiang Mai University Hospital, Chaing Mai 50200, Thailand.

PMID: 23840964 PMCID: PMC3693175 DOI: 10.1155/2013/238783

Abstract

Background. Role of plasmapheresis before thymectomy remains controversial. The aim of this study is to determine the peri-operative and post-operative outcome of a thymectomy between performing and not performing a pre-operative plasmaphreresis. Patients and Methods. A retrospective chart review study was conducted in Chiang Mai University Hospital between January 2006 and December 2011. There were 86 myasthenia patients divided into two groups; Preoperative plasmapheresis group (PPG) and no preoperative plasmapheresis group (NPPG). The primary outcome involved post-operative extubation and the secondary outcome included post-operative complications, 28 day mortality and length of hospital stay. Results. Eighty-six patients were enrolled in this study. The number of patients who had a history of myasthenic crisis at any time or within one month in the PPG was significantly more than those in the NPPG. Muscle power and forced expiratory vital capacity in the NPPG was higher than that in the PPG. The postoperative extubation rate was similar in both groups. After controlling for the propensity score, there were no statistically significant differences in both of primary and secondary outcomes. Conclusion. The results of this study shows no significant differences between both groups in all outcomes, therefore the pre-operative plasmaphresis is not necessary for elective thymectomy.

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