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J Hum Reprod Sci. 2013 Jan;6(1):77-8. doi: 10.4103/0974-1208.112388.

Successful live birth after rescue ICSI following failed fertilization.

Journal of human reproductive sciences

Neeta Singh, Neena Malhotra, Unnati Shende, Abanish Tiwari

Affiliations

  1. Department of Obstetrics and Gynaecology, AIIMS, Ansari Nagar, New Delhi 110 029, India.

PMID: 23869158 PMCID: PMC3713584 DOI: 10.4103/0974-1208.112388

Abstract

In a conventional IVF cycle unexpected complete fertilization failure may occur in 10-25% of infertile women. To overcome this barrier of fertilization failure, some investigators have suggested intracytoplasmic sperm injection (ICSI) on day 1 of an unfertilized mature oocyte, the so called "rescue ICSI". We report a case of fertilization failure followed by rescue ICSI resulting in a live birth. Although the success of rescue ICSI is still questionable, this procedure is worth an attempt in order to give the best chance to the couple in that cycle.

Keywords: Fertlization failure; pregnancy; rescue ICSI

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