Display options
Share it on

Ann Indian Acad Neurol. 2013 Apr;16(2):264-5. doi: 10.4103/0972-2327.112490.

Vogt-Koyanagi-Harada syndrome presenting with encephalopathy.

Annals of Indian Academy of Neurology

Alireza E Naeini, Dana Daneshmand, Farzin Khorvash, Ahmad Chitsaz

Affiliations

  1. Department of Infectious and Tropical Diseases, Isfahan University of Medical Sciences, Isfahan, Iran.

PMID: 23956579 PMCID: PMC3724089 DOI: 10.4103/0972-2327.112490

Abstract

VogtKoyanagi-Harada (VKH) is a rare syndrome affecting tissues with melanocytes. The possibility that VKH syndrome has an autoimmune pathogenesis is supported by the high frequency of human leukocyte antigen-DR4 commonly associated with other autoimmune diseases. Eyes are the main affected organ, resulting in blindness. Brain disease as a late onset event is extremely rare. Here, we are reporting a 57-year-old woman with previously diagnosed VKH syndrome, presenting with a late-onset brain encephalopathy. She was treated with corticosteroids and discharged from hospital with good general condition.

Keywords: Autoimmunity; Vogt-Koyanagi-Harada syndrome; encephalopathy; human leukocyte antigen (HLA)

References

  1. Curr Opin Neurol. 2005 Jun;18(3):323-9 - PubMed
  2. Am J Ophthalmol. 2001 May;131(5):599-606 - PubMed
  3. Curr Eye Res. 2008 Jul;33(7):517-23 - PubMed
  4. AJNR Am J Neuroradiol. 2011 Oct;32(9):E169-71 - PubMed
  5. Int Ophthalmol. 2007 Apr-Jun;27(2-3):195-9 - PubMed
  6. Int Ophthalmol Clin. 2006 Spring;46(2):111-22 - PubMed
  7. J Neurol Neurosurg Psychiatry. 2010 Aug;81(8):941-2 - PubMed
  8. Int Ophthalmol. 2007 Apr-Jun;27(2-3):137-42 - PubMed
  9. Curr Opin Ophthalmol. 2000 Dec;11(6):437-42 - PubMed

Publication Types