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Silveira GF, Buffon A, Bruno AN. New approaches to thyroid hormones and purinergic signaling. J Thyroid Res. 2013;2013:434727doi: 10.1155/2013/434727.
Silveira, G. F., Buffon, A., & Bruno, A. N. (2013). New approaches to thyroid hormones and purinergic signaling. Journal of thyroid research, 2013434727. https://doi.org/10.1155/2013/434727
Silveira, Gabriel Fernandes, et al. "New approaches to thyroid hormones and purinergic signaling." Journal of thyroid research vol. 2013 (2013): 434727. doi: https://doi.org/10.1155/2013/434727
Silveira GF, Buffon A, Bruno AN. New approaches to thyroid hormones and purinergic signaling. J Thyroid Res. 2013;2013:434727. doi: 10.1155/2013/434727. Epub 2013 Jul 17. PMID: 23956925; PMCID: PMC3730180.
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J Thyroid Res. 2013;2013:434727. doi: 10.1155/2013/434727. Epub 2013 Jul 17.

New approaches to thyroid hormones and purinergic signaling.

Journal of thyroid research

Gabriel Fernandes Silveira, Andréia Buffon, Alessandra Nejar Bruno

Affiliations

  1. Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Sul, Porto Alegre (IFRS-POA), Rua Ramiro Barcelos 2777, 90.035-007 Porto Alegre, RS, Brazil.

PMID: 23956925 PMCID: PMC3730180 DOI: 10.1155/2013/434727

Abstract

It is known that thyroid hormones influence a wide variety of events at the molecular, cellular, and functional levels. Thyroid hormones (TH) play pivotal roles in growth, cell proliferation, differentiation, apoptosis, development, and metabolic homeostasis via thyroid hormone receptors (TRs) by controlling the expression of TR target genes. Most of these effects result in pathological and physiological events and are already well described in the literature. Even so, many recent studies have been devoted to bringing new information on problems in controlling the synthesis and release of these hormones and to elucidating mechanisms of the action of these hormones unconventionally. The purinergic system was recently linked to thyroid diseases, including enzymes, receptors, and enzyme products related to neurotransmitter release, nociception, behavior, and other vascular systems. Thus, throughout this text we intend to relate the relationship between the TH in physiological and pathological situations with the purinergic signaling.

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