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Barrado L, Martinez MT, Villa J, et al. Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit. Enferm Infecc Microbiol Clin. 2013;31(10):665-8doi: 10.1016/j.eimc.2013.04.025.
Barrado, L., Martinez, M. T., Villa, J., Orellana, M. �. �., Viedma, E., & Chaves, F. (2013). Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit. Enfermedades infecciosas y microbiologia clinica, 31(10), 665-8. https://doi.org/10.1016/j.eimc.2013.04.025
Barrado, Laura, et al. "Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit." Enfermedades infecciosas y microbiologia clinica vol. 31,10 (2013): 665-8. doi: https://doi.org/10.1016/j.eimc.2013.04.025
Barrado L, Martinez MT, Villa J, Orellana MÁ, Viedma E, Chaves F. Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit. Enferm Infecc Microbiol Clin. 2013 Dec;31(10):665-8. doi: 10.1016/j.eimc.2013.04.025. Epub 2013 Jul 11. PMID: 23850187.
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Enferm Infecc Microbiol Clin. 2013 Dec;31(10):665-8. doi: 10.1016/j.eimc.2013.04.025. Epub 2013 Jul 11.

Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit.

Enfermedades infecciosas y microbiologia clinica

Laura Barrado, M Teresa Martinez, Jennifer Villa, M Ángeles Orellana, Esther Viedma, Fernando Chaves

Affiliations

  1. Servicio de Microbiología Clínica, Hospital Universitario 12 de Octubre, Madrid, Spain.

PMID: 23850187 DOI: 10.1016/j.eimc.2013.04.025

Abstract

INTRODUCTION: The epidemiology of Burkholderia cepacia complex (Bcc) in cystic fibrosis (CF) is not widely known.

METHODS: All CF patients with Bcc between 2002 and 2011 were reviewed, and a molecular analysis of isolates was performed.

RESULTS: The prevalence of Bcc infection was 7.2% (18/250). Molecular analysis of 16 Bcc isolates showed 5 species (7 B. contaminans, 6 B. cepacia, 1 B. cenocepacia, 1 B. multivorans, and 1 B. stabilis) and 13 sequence types. There were no cases of cross-transmission.

CONCLUSION: A high diversity of Bcc species was found in infected CF patients.

Copyright © 2013 Elsevier España, S.L. All rights reserved.

Keywords: Burkholderia cepacia complex; Cystic fibrosis; Epidemiología molecular; Fibrosis quística; Molecular epidemiology

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