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Tian J, Li M, Liao J, et al. Chinese herbal medicine banxiaxiexin decoction treating diabetic gastroparesis: a systematic review of randomized controlled trials. Evid Based Complement Alternat Med. 2013;2013:749495doi: 10.1155/2013/749495.
Tian, J., Li, M., Liao, J., Li, J., & Tong, X. (2013). Chinese herbal medicine banxiaxiexin decoction treating diabetic gastroparesis: a systematic review of randomized controlled trials. Evidence-based complementary and alternative medicine : eCAM, 2013749495. https://doi.org/10.1155/2013/749495
Tian, Jiaxing, et al. "Chinese herbal medicine banxiaxiexin decoction treating diabetic gastroparesis: a systematic review of randomized controlled trials." Evidence-based complementary and alternative medicine : eCAM vol. 2013 (2013): 749495. doi: https://doi.org/10.1155/2013/749495
Tian J, Li M, Liao J, Li J, Tong X. Chinese herbal medicine banxiaxiexin decoction treating diabetic gastroparesis: a systematic review of randomized controlled trials. Evid Based Complement Alternat Med. 2013;2013:749495. doi: 10.1155/2013/749495. Epub 2013 Jul 11. PMID: 23935681; PMCID: PMC3725710.
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Evid Based Complement Alternat Med. 2013;2013:749495. doi: 10.1155/2013/749495. Epub 2013 Jul 11.

Chinese herbal medicine banxiaxiexin decoction treating diabetic gastroparesis: a systematic review of randomized controlled trials.

Evidence-based complementary and alternative medicine : eCAM

Jiaxing Tian, Min Li, Jiangquan Liao, Junling Li, Xiaolin Tong

Affiliations

  1. Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beixiange 5, Xicheng District, Beijing 100053, China ; Graduate School, Beijing University of TCM, Beijing 100029, China.

PMID: 23935681 PMCID: PMC3725710 DOI: 10.1155/2013/749495

Abstract

Objective. To assess the current clinical evidence of Banxiaxiexin decoction for diabetic gastroparesis (DGP). Methods. Electronic databases were searched until December 2012. No language limitations were applied. We included RCTs using Banxiaxiexin decoction/modified Banxiaxiexin decoction for DGP. No restriction for the control group except acupuncture. Applying clinical effective rate as the main outcome index. Data extraction, analyses and quality assessment were conducted according to the Cochrane review standards. Results. 16 RCTs involving 1302 patients were finally identified, and the methodological quality was evaluated as generally low. The data showed that the effect of Banxiaxiexin decoction (BXXD) for DGP was superior to the control group (n = 1302, RR 1.23, 95% CI 1.17 to 1.29, Z = 8.04, P < 0.00001). Only one trial recorded adverse events, no obvious adverse event occurred. Conclusions. Banxiaxiexin decoction could regain the gastric emptying rate and improve diabetic gastrointestinal symptoms. However, the methodological quality of included studies is low, and long term efficacy and safety are still uncertain, which indicates that the findings above should be read with caution. Thereby, well-designed, large-scale, and high-quality randomized controlled clinical trials with scientific rigor are warranted for stronger evidence in future research.

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