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J Tehran Heart Cent. 2013 Apr;8(2):65-9. Epub 2013 Apr 28.

Noninvasive localization of accessory pathways in patients with wolff-Parkinson-white syndrome: a strain imaging study.

The journal of Tehran Heart Center

Maryam Esmaeilzadeh, Mohammad Taghi Salehi Omran, Majid Maleki, Majid Haghjoo, Feridoun Noohi, Zahra Ojaghi Haghighi, Anita Sadeghpour, Paridokht Nakhostin Davari, Hooman Bakhshandeh Abkenar

Affiliations

  1. Echocardiography Research Center, Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

PMID: 23967027 PMCID: PMC3740111

Abstract

BACKGROUND: Noninvasive techniques for the localization of the accessory pathways (APs) might help guide mapping procedures and ablation techniques. We sought to examine the diagnostic accuracy of strain imaging for the localization of the APs in Wolff-Parkinson-White syndrome.

METHODS: We prospectively studied 25 patients (mean age = 32 ± 17 years, 58.3% men) with evidence of pre-excitation on electrocardiography (ECG). Electromechanical interval was defined as the time difference between the onset of delta wave and the onset of regional myocardial contraction. Time differences between the onset of delta wave (δ) and the onset of regional myocardial contraction (δ-So), peak systolic motion (δ-Sm), regional strain (δ-ε), peak strain (δ-εp), and peak strain rate (δ-SRp) were measured.

RESULTS: There was a significant difference between time to onset of delta wave to onset of peak systolic motion (mean ± SD) in the AP location (A) and normal segments (B) versus that in the normal volunteers (C) [A: (57.08 ± 23.88 msec) vs. B: (75.20 ± 14.75) vs. C: (72.9 0 ± 11.16); p value (A vs. B) = 0.004 and p value (A vs. C) = 0.18] and [A: (49.17 ± 35.79) vs. B: (67.60 ± 14.51) vs. C: (67.40 ± 6.06 msec); p value (A vs. B) < 0.001 and p value (A vs. C) = 0.12, respectively].

CONCLUSION: Our study showed that strain imaging parameters [(δ-So) and (δ-Strain)] are superior to the ECG in the localization of the APs (84% vs. 76%).

Keywords: Ablation; Accessory atrioventricular bundle; Diagnosis; Wolff-Parkinson-White syndrome

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