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Singh VP, Singh N, Jaggi AS. A review on renal toxicity profile of common abusive drugs. Korean J Physiol Pharmacol. 2013;17(4):347-57doi: 10.4196/kjpp.2013.17.4.347.
Singh, V. P., Singh, N., & Jaggi, A. S. (2013). A review on renal toxicity profile of common abusive drugs. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 17(4), 347-57. https://doi.org/10.4196/kjpp.2013.17.4.347
Singh, Varun Parkash, et al. "A review on renal toxicity profile of common abusive drugs." The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol. 17,4 (2013): 347-57. doi: https://doi.org/10.4196/kjpp.2013.17.4.347
Singh VP, Singh N, Jaggi AS. A review on renal toxicity profile of common abusive drugs. Korean J Physiol Pharmacol. 2013 Aug;17(4):347-57. doi: 10.4196/kjpp.2013.17.4.347. Epub 2013 Jul 30. PMID: 23946695; PMCID: PMC3741492.
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Korean J Physiol Pharmacol. 2013 Aug;17(4):347-57. doi: 10.4196/kjpp.2013.17.4.347. Epub 2013 Jul 30.

A review on renal toxicity profile of common abusive drugs.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Varun Parkash Singh, Nirmal Singh, Amteshwar Singh Jaggi

Affiliations

  1. Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala-147002, India.

PMID: 23946695 PMCID: PMC3741492 DOI: 10.4196/kjpp.2013.17.4.347

Abstract

Drug abuse has become a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present review discusses the renal toxicity profile and possible mechanisms of commonly abused drugs including morphine, heroin, cocaine, nicotine, caffeine and alcohol.

Keywords: Caffeine; Cocaine; Heroin; Morphine; Renal failure

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