Display options
Cite
Kang SJ, Yoon KH, Hwang JB. Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis. Pediatr Gastroenterol Hepatol Nutr. 2013;16(1):61-4doi: 10.5223/pghn.2013.16.1.61.
Kang, S. J., Yoon, K. H., & Hwang, J. B. (2013). Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis. Pediatric gastroenterology, hepatology & nutrition, 16(1), 61-4. https://doi.org/10.5223/pghn.2013.16.1.61
Kang, Seok-Jin, et al. "Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis." Pediatric gastroenterology, hepatology & nutrition vol. 16,1 (2013): 61-4. doi: https://doi.org/10.5223/pghn.2013.16.1.61
Kang SJ, Yoon KH, Hwang JB. Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis. Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):61-4. doi: 10.5223/pghn.2013.16.1.61. Epub 2013 Mar 31. PMID: 24010108; PMCID: PMC3746049.
Copy Download .nbib Format: NLM
Share it on

Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):61-4. doi: 10.5223/pghn.2013.16.1.61. Epub 2013 Mar 31.

Epstein-barr virus infection with acute pancreatitis associated with cholestatic hepatitis.

Pediatric gastroenterology, hepatology & nutrition

Seok-Jin Kang, Ka-Hyun Yoon, Jin-Bok Hwang

Affiliations

  1. Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea.

PMID: 24010108 PMCID: PMC3746049 DOI: 10.5223/pghn.2013.16.1.61

Abstract

Infection-induced acute hepatitis complicated with acute pancreatitis is associated with hepatitis A virus, hepatitis B virus or hepatitis E virus. Although rare, Epstein-Barr virus (EBV) infection should be considered also in the differential diagnosis if the patient has acute hepatitis combined with pancreatitis. We report a case of EBV infection with cholestatic hepatitis and pancreatitis with review of literature. An 11-year-old female was admitted due to 1-day history of abdominal pain and vomiting without any clinical symptoms of infectious mononucleosis. Diagnosis of reactivated EBV infection was made by the positive result of viral capsid antigen (VCA) IgM, VCA IgG, Epstein-Barr nuclear antigen and heterophile antibody test. We performed serologic tests and magnetic resonance cholangiopancreatography to exclude other viral or bacterial infection, autoimmune disorder, and structural problems. The patient's symptoms recovered rapidly and blood chemistry returned to normal with conservative treatment similar to previously reported cases.

Keywords: Cholestasis; Epstein-Barr virus; Hepatitis; Pancreatitis

References

  1. Pancreas. 2008 May;36(4):424-7 - PubMed
  2. Int J Infect Dis. 2008 Mar;12(2):227-9 - PubMed
  3. Isr J Med Sci. 1982 Jun;18(6):709-10 - PubMed
  4. J Infect. 2005 Aug;51(2):E57-60 - PubMed
  5. Eur J Intern Med. 2011 Feb;22(1):73-6 - PubMed
  6. World J Gastroenterol. 2007 Nov 21;13(43):5741-4 - PubMed
  7. Pancreatology. 2006;6(1-2):141-4 - PubMed
  8. Gastroenterology. 1981 Dec;81(6):998-1005 - PubMed
  9. Am J Gastroenterol. 1999 Aug;94(8):2292-5 - PubMed
  10. N Engl J Med. 1966 Aug 11;275(6):322-3 - PubMed
  11. South Med J. 1969 Mar;62(3):359-60 - PubMed
  12. Pediatr Infect Dis. 1983 Jul-Aug;2(4):312-3 - PubMed

Publication Types