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Hellen EH, Dana SK, Kurths J, et al. Noise-aided logic in an electronic analog of synthetic genetic networks. PLoS One. 2013;8(10):e76032doi: 10.1371/journal.pone.0076032.
Hellen, E. H., Dana, S. K., Kurths, J., Kehler, E., & Sinha, S. (2013). Noise-aided logic in an electronic analog of synthetic genetic networks. PloS one, 8(10), e76032. https://doi.org/10.1371/journal.pone.0076032
Hellen, Edward H, et al. "Noise-aided logic in an electronic analog of synthetic genetic networks." PloS one vol. 8,10 (2013): e76032. doi: https://doi.org/10.1371/journal.pone.0076032
Hellen EH, Dana SK, Kurths J, Kehler E, Sinha S. Noise-aided logic in an electronic analog of synthetic genetic networks. PLoS One. 2013 Oct 04;8(10):e76032. doi: 10.1371/journal.pone.0076032. eCollection 2013. PMID: 24124531; PMCID: PMC3790844.
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PLoS One. 2013 Oct 04;8(10):e76032. doi: 10.1371/journal.pone.0076032. eCollection 2013.

Noise-aided logic in an electronic analog of synthetic genetic networks.

PloS one

Edward H Hellen, Syamal K Dana, Jürgen Kurths, Elizabeth Kehler, Sudeshna Sinha

Affiliations

  1. Department of Physics and Astronomy, University of North Carolina Greensboro, Greensboro, North Carolina, United States of America.

PMID: 24124531 PMCID: PMC3790844 DOI: 10.1371/journal.pone.0076032

Abstract

We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and numerical prediction, with the circuit allowing for robust logic operations in an optimal window of noise. Namely, the input-output characteristics of a logic gate is reproduced faithfully under moderate noise, which is a manifestation of the phenomenon known as Logical Stochastic Resonance. The two dynamical variables in the system yield complementary logic behaviour simultaneously. The system is easily morphed from AND/NAND to OR/NOR logic.

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