Display options
Cite
Pinto Cda P, Rodrigues VD, Pinto Fda P, et al. Antimicrobial activity of lippia species from the brazilian semiarid region traditionally used as antiseptic and anti-infective agents. Evid Based Complement Alternat Med. 2013;2013:614501doi: 10.1155/2013/614501.
Pinto, C. d. a. . P., Rodrigues, V. D., Pinto, F. d. a. . P., Pinto, R. d. a. . P., Uetanabaro, A. P., Pinheiro, C. S., Gadea, S. F., Silva, T. R., & Lucchese, A. M. (2013). Antimicrobial activity of lippia species from the brazilian semiarid region traditionally used as antiseptic and anti-infective agents. Evidence-based complementary and alternative medicine : eCAM, 2013614501. https://doi.org/10.1155/2013/614501
Pinto, Cristiana da Purificação, et al. "Antimicrobial activity of lippia species from the brazilian semiarid region traditionally used as antiseptic and anti-infective agents." Evidence-based complementary and alternative medicine : eCAM vol. 2013 (2013): 614501. doi: https://doi.org/10.1155/2013/614501
Pinto Cda P, Rodrigues VD, Pinto Fda P, Pinto Rda P, Uetanabaro AP, Pinheiro CS, Gadea SF, Silva TR, Lucchese AM. Antimicrobial activity of lippia species from the brazilian semiarid region traditionally used as antiseptic and anti-infective agents. Evid Based Complement Alternat Med. 2013;2013:614501. doi: 10.1155/2013/614501. Epub 2013 Sep 10. PMID: 24109492; PMCID: PMC3784154.
Copy Download .nbib Format: NLM
Share it on

Evid Based Complement Alternat Med. 2013;2013:614501. doi: 10.1155/2013/614501. Epub 2013 Sep 10.

Antimicrobial activity of lippia species from the brazilian semiarid region traditionally used as antiseptic and anti-infective agents.

Evidence-based complementary and alternative medicine : eCAM

Cristiana da Purificação Pinto, Velize Dias Rodrigues, Fernanda da Purificação Pinto, Renata da Purificação Pinto, Ana Paula Trovatti Uetanabaro, Carla Santos Ribeiro Pinheiro, Suzana Ferreira Magalhães Gadea, Tânia Regina Dos Santos Silva, Angélica Maria Lucchese

Affiliations

  1. Laboratório de Química de Produtos Naturais e Bioativos, Departamento de Ciências Exatas, Universidade Estadual de Feira de Santana, Avenida Transnordestina S/N, Bairro Novo Horizonte, Campus Universitário, 44036-900 Feira de Santana, BA, Brazil.

PMID: 24109492 PMCID: PMC3784154 DOI: 10.1155/2013/614501

Abstract

Lippia origanoides Kunth, Lippia alnifolia Schauer, and Lippia thymoides Martius and Schauer are shrubs used in the traditional Brazilian medicine as antiseptics, as well as in the treatment of infectious diseases. This study was designed to investigate the antibacterial and antifungal activities of the methanolic extracts of these species, as new potential sources of antimicrobial drugs. The antimicrobial activity of methanolic extracts was investigated against resistant yeasts and bacteria by agar disk diffusion. Then, the MIC determination of the most active species and its fractions in hexane, dichloromethane, ethyl acetate, and water was performed. By the agar diffusion assay, all species were active against at least two microorganisms, giving evidence to support their use in the popular medicine. L. origanoides leaves exhibited the widest antimicrobial action, inhibiting the growth of two Gram-positive bacteria and two yeasts; this activity was also confirmed by the MIC evaluation. The fractionation of L. origanoides crude extracts improved the activity in spectrum and intensity. The results obtained in this study indicate that L. origanoides may be a promising alternative in the treatment of bacterial and fungal infections and in the seeking of new antimicrobial drugs.

References

  1. J Ethnopharmacol. 2001 Aug;76(3):201-14 - PubMed
  2. Clin Microbiol Rev. 2007 Jan;20(1):133-63 - PubMed
  3. J Ethnopharmacol. 2011 Oct 11;137(3):1334-6 - PubMed
  4. Mol Microbiol. 2007 Oct;66(2):279-90 - PubMed
  5. J Ethnopharmacol. 2010 Oct 28;132(1):101-8 - PubMed
  6. Clin Microbiol Rev. 1999 Oct;12(4):564-82 - PubMed
  7. J Bacteriol. 2001 Oct;183(19):5709-17 - PubMed

Publication Types