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Grosskopf R, Feldmann H. Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits I, II and III, ATPase subunit 6, and several tRNA genes. Curr Genet. 1981;4(2):151-8doi: 10.1007/BF00365694.
Grosskopf, R., & Feldmann, H. (1981). Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits I, II and III, ATPase subunit 6, and several tRNA genes. Current genetics, 4(2), 151-8. https://doi.org/10.1007/BF00365694
Grosskopf, R, and Feldmann, H. "Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits I, II and III, ATPase subunit 6, and several tRNA genes." Current genetics vol. 4,2 (1981): 151-8. doi: https://doi.org/10.1007/BF00365694
Grosskopf R, Feldmann H. Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits I, II and III, ATPase subunit 6, and several tRNA genes. Curr Genet. 1981 Nov;4(2):151-8. doi: 10.1007/BF00365694. PMID: 24185961.
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Curr Genet. 1981 Nov;4(2):151-8. doi: 10.1007/BF00365694.

Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits I, II and III, ATPase subunit 6, and several tRNA genes.

Current genetics

R Grosskopf, H Feldmann

Affiliations

  1. Institut für Physiologische Chemie, Physikalische Biochemie und Zellbiologie der Universität München, Goethestrasse 33, 8000, München 2, Germany.

PMID: 24185961 DOI: 10.1007/BF00365694

Abstract

The sequence of a 6.24 kb DNA segment of the mitochondrial genome from rat liver has been determined. It comprises several genes coding for mitochondrial protein subunits and five tRNA genes in the following order: cytochrome oxidase subunit I - tRNA (UCN) (Ser) -tRNA(Asp) - cytochrome oxidase subunit II - tRNALys -ATPase subunit - cytochrome oxidase subunit III -tRNA(Gly) - potential open reading frame - tRNA(Arg) -two potential open reading frames. The tRNA genes were detected by a computer search programme. The assignments for the protein coding sequences were made through comparison with known sequences, mainly from the yeast mitochondrial proteins (e.g. Bonitz et al. 1980). Our data are discussed with regard to the features of gene arrangement, codon usage, and tRNA structure in mammalian mitochondria (Anderson et al. 1981).

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