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Crockett JS, Gross ML, Christie WW, et al. Collisional activation of a series of homoconjugated octadecadienoic acids with fast atom bombardment and tandem mass spectrometry. J Am Soc Mass Spectrom. 1990;1(2):183-91doi: 10.1016/1044-0305(90)85055-Q.
Crockett, J. S., Gross, M. L., Christie, W. W., & Holman, R. T. (1990). Collisional activation of a series of homoconjugated octadecadienoic acids with fast atom bombardment and tandem mass spectrometry. Journal of the American Society for Mass Spectrometry, 1(2), 183-91. https://doi.org/10.1016/1044-0305(90)85055-Q
Crockett, J S, et al. "Collisional activation of a series of homoconjugated octadecadienoic acids with fast atom bombardment and tandem mass spectrometry." Journal of the American Society for Mass Spectrometry vol. 1,2 (1990): 183-91. doi: https://doi.org/10.1016/1044-0305(90)85055-Q
Crockett JS, Gross ML, Christie WW, Holman RT. Collisional activation of a series of homoconjugated octadecadienoic acids with fast atom bombardment and tandem mass spectrometry. J Am Soc Mass Spectrom. 1990 Apr;1(2):183-91. doi: 10.1016/1044-0305(90)85055-Q. PMID: 24248747.
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J Am Soc Mass Spectrom. 1990 Apr;1(2):183-91. doi: 10.1016/1044-0305(90)85055-Q.

Collisional activation of a series of homoconjugated octadecadienoic acids with fast atom bombardment and tandem mass spectrometry.

Journal of the American Society for Mass Spectrometry

J S Crockett, M L Gross, W W Christie, R T Holman

Affiliations

  1. Midwest Center for Mass Spectrometry, Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.

PMID: 24248747 DOI: 10.1016/1044-0305(90)85055-Q

Abstract

High-energy collisional activation (CA) of long-chain fatty acid ions induces decompositions that occur remote from the charge site. These charge-remote fragmentations (CRFs) have been shown to provide much structural information. In this report, the CRF of a continuous series of 12 homoconjugated octadecadienoic acids was studied with fast atom bombardment and tandem mass spectrometry. Each fatty acid was desorbed as the carboxylate anion, [M - H](-), the dilithiated species, [M - H+2Li](+), or the bariated species, [M - H+Ba](+), giving three ways of localizing the charge. A characteristic pattern is generated for CRF of the 1,4-diene functional group, and this allows for the rapid identification of the functional group and its location on the chain. Minor variations of this pattern are observed for the different ionic precursors and for different locations of the double bonds. Furthermore, there are a few complications from different types of charge-proximate reactions, especially of the fatty acid carboxylates.

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