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Kaczmarski M, Cudowska B, Sawicka-Żukowska M, et al. Supplementation with long chain polyunsaturated fatty acids in treatment of atopic dermatitis in children. Postepy Dermatol Alergol. 2013;30(2):103-7doi: 10.5114/pdia.2013.34160.
Kaczmarski, M., Cudowska, B., Sawicka-Żukowska, M., & Bobrus-Chociej, A. (2013). Supplementation with long chain polyunsaturated fatty acids in treatment of atopic dermatitis in children. Postepy dermatologii i alergologii, 30(2), 103-7. https://doi.org/10.5114/pdia.2013.34160
Kaczmarski, Maciej, et al. "Supplementation with long chain polyunsaturated fatty acids in treatment of atopic dermatitis in children." Postepy dermatologii i alergologii vol. 30,2 (2013): 103-7. doi: https://doi.org/10.5114/pdia.2013.34160
Kaczmarski M, Cudowska B, Sawicka-Żukowska M, Bobrus-Chociej A. Supplementation with long chain polyunsaturated fatty acids in treatment of atopic dermatitis in children. Postepy Dermatol Alergol. 2013 Apr;30(2):103-7. doi: 10.5114/pdia.2013.34160. Epub 2013 Apr 12. PMID: 24278056; PMCID: PMC3834680.
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Postepy Dermatol Alergol. 2013 Apr;30(2):103-7. doi: 10.5114/pdia.2013.34160. Epub 2013 Apr 12.

Supplementation with long chain polyunsaturated fatty acids in treatment of atopic dermatitis in children.

Postepy dermatologii i alergologii

Maciej Kaczmarski, Beata Cudowska, Małgorzata Sawicka-Żukowska, Anna Bobrus-Chociej

Affiliations

  1. Department of Pediatrics, Gastroenterology and Allergology, Medical University of Bialystok, Poland. Head: Prof. Maciej Kaczmarski MD, PhD.

PMID: 24278056 PMCID: PMC3834680 DOI: 10.5114/pdia.2013.34160

Abstract

Some recent studies indicate that unsaturated fatty acids, components of cellular membranes and precursors of immunomodulators, play a significant role in the pathogenesis of some symptoms of atopic dermatitis. Since they cannot be synthesized by the human body, they must be provided with nutrition as the so called exogenous fatty acids: linoleic (a precursor of arachidonic acid) and α-linolenic acid (a precursor of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)). Their deficiency facilitates the development of some disorders, e.g. of the cardiovascular system or of the nervous system, or becomes the cause of intensification of ailments in their course e.g. pruritus and dryness in atopic dermatitis. Though clinical examinations to date confirm the efficacy of fatty acid supplementation in treatment of atopic dermatitis, their results are not explicit.

Keywords: atopic dermatitis; polyunsaturated fatty acids

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