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Curr Genet. 1979 Dec;1(1):9-12. doi: 10.1007/BF00413302.

The monocistronic nature of ribosomal protein genes in yeast.

Current genetics

C Gorenstein, J R Warner

Affiliations

  1. Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, 10461, Bronx, New York, USA.

PMID: 24190803 DOI: 10.1007/BF00413302

Abstract

The synthesis of thirty five ribosomal proteins has been studied in Saccharomyces cerevisiae using a temperature sensitive mutant blocked in the initiation of polypeptides. The synthesis of all the ribosomal proteins was nearly equally affected by the block. This absence of polarity, together with previous genetic and biochemical data, indicates that eukaryotic ribosomal proteins are coded by monocistronic mRNAs.

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