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Black WC, Krafsur ES. A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. Theor Appl Genet. 1985;70(5):491-6doi: 10.1007/BF00305981.
Black, W. C., & Krafsur, E. S. (1985). A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 70(5), 491-6. https://doi.org/10.1007/BF00305981
Black, W C, and Krafsur, E S. "A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 70,5 (1985): 491-6. doi: https://doi.org/10.1007/BF00305981
Black WC, Krafsur ES. A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. Theor Appl Genet. 1985 Aug;70(5):491-6. doi: 10.1007/BF00305981. PMID: 24253058.
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Theor Appl Genet. 1985 Aug;70(5):491-6. doi: 10.1007/BF00305981.

A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

W C Black, E S Krafsur

Affiliations

  1. Department of Entomology, Iowa State University, 50011, Ames, IA, USA.

PMID: 24253058 DOI: 10.1007/BF00305981

Abstract

A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in linkage disequilibrium into within- and between-subpopulation components. Output obtained from analysis of allozyme data collected from natural subpopulations of the house fly (Musca domestica L.) are included to illustrate features of the program.

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