Display options
Share it on

Biol Trace Elem Res. 1987 Apr;12(1):3-16. doi: 10.1007/BF02796662.

Role of nuclear analytical probe techniques in biological trace-element research.

Biological trace element research

K W Jones, J G Pounds

Affiliations

  1. Department of Applied Science, Brookhaven National Laboratory, 11973, Upton, NY.

PMID: 24254585 DOI: 10.1007/BF02796662

Abstract

Many biomedical experiments require the qualitative and quantitative localization of trace elements with high sensitivity and good spatial resolution. The feasibility of measuring the chemical form of the elements, the time course of trace element metabolism, and conducting experiments in living biological systems are also important requirements for biological trace element research. Nuclear analytical techniques that employ ion or photon beams have grown in importance in the past decade and have led to several new experimental approaches. Some of the important features of these methods are reviewed here along with their role in trace element research. Examples of their use are given to illustrate potential for new research directions. It is emphasized that the effective application of these methods necessitates a closely integrated multidisciplinary scientific team.

References

  1. Biol Trace Elem Res. 1987 Apr;12(1):231-45 - PubMed
  2. Neurotoxicology. 1983 Fall;4(3):177-88 - PubMed
  3. Science. 1974 Oct 25;186(4161):361-3 - PubMed
  4. Neurotoxicology. 1983 Fall;4(3):23-33 - PubMed
  5. Biol Trace Elem Res. 1987 Apr;12(1):153-9 - PubMed

Publication Types