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Yu SY, Chu YJ, Gong XL, et al. Regional variation of cancer mortality incidence and its relation to selenium levels in China. Biol Trace Elem Res. 1985;7(1):21-9doi: 10.1007/BF02916544.
Yu, S. Y., Chu, Y. J., Gong, X. L., Hou, C., Li, W. G., Gong, H. M., & Xie, J. R. (1985). Regional variation of cancer mortality incidence and its relation to selenium levels in China. Biological trace element research, 7(1), 21-9. https://doi.org/10.1007/BF02916544
Yu, S Y, et al. "Regional variation of cancer mortality incidence and its relation to selenium levels in China." Biological trace element research vol. 7,1 (1985): 21-9. doi: https://doi.org/10.1007/BF02916544
Yu SY, Chu YJ, Gong XL, Hou C, Li WG, Gong HM, Xie JR. Regional variation of cancer mortality incidence and its relation to selenium levels in China. Biol Trace Elem Res. 1985 Feb;7(1):21-9. doi: 10.1007/BF02916544. PMID: 24258872.
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Biol Trace Elem Res. 1985 Feb;7(1):21-9. doi: 10.1007/BF02916544.

Regional variation of cancer mortality incidence and its relation to selenium levels in China.

Biological trace element research

S Y Yu, Y J Chu, X L Gong, C Hou, W G Li, H M Gong, J R Xie

Affiliations

  1. Cancer Institute, Chinese Academy of Medical Sciences, Beijing, China.

PMID: 24258872 DOI: 10.1007/BF02916544

Abstract

The epidemiological relationship between selenium level and age-adjusted human cancer mortality (incidence) was studied in 24 regions located in eight provinces of China. Statistically significant inverse correlation was found between age-adjusted total cancer death rates and selenium levels in whole blood from local residents. In the areas with high selenium levels, there was significantly lower mortality in both males and females from cancer of the stomach and esophagus. In addition, an inverse correlation between regional distribution of liver cancer incidence and selenium contents in blood and grains in Qidong county, an area with high risk of hepatoma, was observed. With the intention of providing selenium supplements to residents living in low selenium regions, the selenium content in grains was raised by means of foliar spraying of crops with Na2SeO3 solution.

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