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Case Rep Urol. 2013;2013:931893. doi: 10.1155/2013/931893. Epub 2013 Oct 20.

Sarcomatoid carcinoma of male urethra with bone and lung metastases presenting as urethral stricture.

Case reports in urology

Niraj Badhiwala, Robert Chan, Hai-Jun Zhou, Steven Shen, Michael Coburn

Affiliations

  1. Washington University School of Medicine, St. Louis, MO 63110, USA.

PMID: 24228184 PMCID: PMC3817800 DOI: 10.1155/2013/931893

Abstract

A 57-year-old man who presented with urinary retention was found to have a sarcomatoid carcinoma of the urethra. Evaluation with CT scan of the abdomen and pelvis revealed multiple pulmonary nodules and osteolytic lesions of left posterior ribs. After external beam radiation therapy and six cycles of systemic chemotherapy, patient underwent a surgical resection of the urethral cancer. After his surgery, patient was also found to have multiple brain metastases and underwent whole brain radiation therapy, nine months after his initial diagnosis. Sarcomatoid carcinomas of the genitourinary tract are extremely rare tumors that require a very aggressive, multimodal treatment approach.

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