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Marks RW, Robertson CA. Efficient estimation of allelic and genotypic proportions for electrophoretic loci. Theor Appl Genet. 1983;65(3):197-200doi: 10.1007/BF00308065.
Marks, R. W., & Robertson, C. A. (1983). Efficient estimation of allelic and genotypic proportions for electrophoretic loci. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 65(3), 197-200. https://doi.org/10.1007/BF00308065
Marks, R W, and Robertson, C A. "Efficient estimation of allelic and genotypic proportions for electrophoretic loci." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 65,3 (1983): 197-200. doi: https://doi.org/10.1007/BF00308065
Marks RW, Robertson CA. Efficient estimation of allelic and genotypic proportions for electrophoretic loci. Theor Appl Genet. 1983 May;65(3):197-200. doi: 10.1007/BF00308065. PMID: 24263414.
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Theor Appl Genet. 1983 May;65(3):197-200. doi: 10.1007/BF00308065.

Efficient estimation of allelic and genotypic proportions for electrophoretic loci.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

R W Marks, C A Robertson

Affiliations

  1. Department of Biology, Villanova University, 19085, Villanova, PA, USA.

PMID: 24263414 DOI: 10.1007/BF00308065

Abstract

The efficiency of estimating allelic and genotypic frequencies at allozyme loci can often be increased by running more than one individual simultaneously in each sample slot in a gel. Increased precision in estimating allelic frequencies is always possible if Hardy-Weinberg proportions can be assumed. However, if Hardy-Weinberg cannot be assumed, estimates of both allelic and genotypic frequencies can be improved for loci with hybrid dimers, but not for loci without them. The efficiency of all estimators depends jointly on allele frequencies and the number of individuals run simultaneously.

References

  1. Genetics. 1978 Aug;89(4):793-810 - PubMed
  2. Evolution. 1970 Dec;24(4):807-815 - PubMed
  3. Ann Hum Genet. 1976 May;39(4):383-411 - PubMed

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